Reishi Spore Powder

Ganoderma Lucidum Spore powder
【Botanical Source】: Ganoderma Lucidum
【Material used】: Shell-broken spore powder
【Specification】: 4% triterpenoid, 300 mesh, shell-broken ratio>98%
【Appearance】: Brownish red fine powder
【Benefits】: Promote immunity, lower blood sugar and pressure, and prevent cardiovascular and cerebrovascular diseases.

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INQUIRY

Brief Introduction
Ganoderma Lucidum(Ling Zhi, Reishi mushroom) is regarded as one of the most treasures in traditional Chinese medicine. There are a lot of proven documents including Chinese pharmaceutical studies and modern clinical research indicate that Ganoderma Lucidum is helpful to increase energy, ease fatigue and help to prolong human life. In two famous ancient Chinese medical masterpieces, “Sheng Nong’s Herbal Classic”, and “Compendium of Materia Medica”, written in the period of Ming Dynasty from A.D 1271 to A.D. 1368, provides detailed descriptions of the benefits of Ganoderma Lucidum. And in many other Chinese ancient medical books, Ganoderma Lucidum was mentioned with many contents because of its extraordinary health effects with an application history for several thousand years.

Ganoderma Lucidum Spores are the seeds of Ganoderma Lucidum mushroom plant that are released from the fruit body when the fungus ripens. Biologically, these seeds are called spores. And commercially they are called “Ganoderma Lucidum Spore Powder.” Ganoderma Lucidum spores are a type of dark brownnish powder with light weight and naturally spray out of the ganoderma cap into the air when the Ganoderma Lucidum grows to about 6-7 months.  Many people may question why there is no mention of ganoderma spore in ancient medical books. This is because Spores Powder is a fairly new “discovery”. And Spores produced by common species or rather wild Ganoderma Lucidum plant are too miniscule to be viable for commercial production. Furthermore, the ravaging rain and wind also exacerbated this situation by damaging and scattering the Spores that were released. Hence, there was never any mentioned of the said Spores as having been used for healing in the authoritative ancient Pharmacopoeia “Sheng Nong Pern T’sao Jing”. It was only until recently when new species of “Spores” Ganoderma Lucidum plant that can produce Spores in profusion was successfully cultured and grown that now made it possible for Spores Powder to be made available on a commercial scale. 

Ganoderma Lucidum spores spray generally lasts for a continuous period of about 10 days. Ganoderma Lucidum spores usually are collected by using paper bags to cover the whole ganoderma cap during the period when it sprays the spores.  With many lab researches and studies in recent years, Ganoderma Lucidum spores are highly recognized by world scientists as the essence of Ganoderma Lucidum. Ganoderma Lucidum spores are a part of the mushroom, but it is the most significant composition of the Ganoderma Lucidum mushroom according to the current studies. Many Chinese TCM doctors highly recommend Ganoderma Lucidum spores products to those who are suffering from poor immune system and metabolism system disorders in order to achieve a full body recovery. That is becauseGanoderma Lucidum spores contain rich nutrition good for human health, including polysaccharides, triterpenoids compound, trace elements and so on.

Collection of Ganoderma Lucidum Spores

Preliminary Judgement on Ganoderma Spores Powder Quality
1. Observe the appearance: high quality ganoderma spore powder is in dark brown reddish and may cake because the spore powder is rich in spore oil.
2. Entwist with fingers: high quality ganoderma spore powder is with above 98% shell-broken ratio, thus it is with a fine and smooth touch.
3. Test the spore oil contained. Take out a piece of tissue and get some ganoderma spore powder on it; then fold and press the tissue and oil will be left on the unfold tissue.
4. Tate: With a smooth touch and a slight bitter taste in mouth.

Major Components of Ganoderma Lucidum Spores
Scientific studies indicate that Ganoderma spore contain about a thousand of active pharmaceutical components, such as 
Ganoderma Lucidum polysaccharides, Ganoderma Lucidum triterpenes, Ganoderma Lucidum polypeptides, 16 types of amino acids (7 of which are indispensable to humans), proteins, steroids, mannitol, coumarin, alkaloids, organic acids (mainly fumarate), and trace elements such as Ge, P, Fe, Ca, Mn, Zn, etc.  Among all these substances, triterpenoidspolysaccharide, nucleotides, amino-acid, micro-element, organic-germanium and alkaloids endow the Ganoderma Lucidum Spores with above mentioned physiological activities.

Triterpenoids compound
The trierpenoide compound includes Granoderma Lucidum acid. Ganoderma Lucidum spore acid, Red Lingzhi spore lactones etc. tetracyclic or pentacyclic triterpenoids, belongs to high-oxidized steral by-derivatives. Currently, about one hundred and eight triterpenoid compounds have been discovered by the scientist in the world.

Shell-broken or Shell-unbroken Ganoderma Lucidum Spore Powder
The surface of the Ganoderma lucidum spore has a double layer of hard shell, the active ingredient of the spore powder contained in it, which is not easy to be absorbed by human body. There are many different kinds of cell-wall break technology, such as enzyme hydrolysis, chemical method, and physical method.  Among all these methods, “Pneumatic cracker(High-speed Airflow Cracker)” is the most chosen way because this (cold) processing method ensures breaking the shell of up to 98% of the spores successfully; most importantly, it also preserves all of its bio-active substances are not destroyed.

Some arguments indicate that the shell-broken prodcess of Granoderma Lucidum spore may cause the exposure of protoplasm in the air and result in oxidation of inside bio-active substances. Based on many studies and experiments, this perspective is not correct and the reasons are discussed in below 3 aspects:
1). Ganoderma Lucidum spore consists of highly oxidized organic compounds and combinations, thus it is hard to combine more oxygen atoms (ions) from chemical perspective.
2). Ganoderma Lucidum spore is covered by two husks/walls and the inner layer is made of chitin which is difficult to be digested in human body. Comparison of the excrement from two group of experimenters, more complete Ganoderma Lucidum spores were found for those who took shell-unbroken Ganoderma Lucidum spore powder.
3).With reference to the application history around 10 years in China, Japan and Korea, shell-broken process has been the optimal method to make most of Ganoderma Lucidum spore. And many experimental data indicate that the absorption rate is much higher for shell-broken spores than unbroken one. Meanwhile, one report in Japan showed that polysaccharide in shell-broken Ganoderma Lucidum spore absorbed by the human body is 9.3 times higher than that of decocted one.

Therefore, current studies could prove shell-broken Ganoderma Lucidum spores powder could help the absorption of inside active ingredients and will not cause damage in the whole process.

Ganoderma Lucidum Spore Benefits
1). Stimulating anti-tumor response./ Reducing percentage of new blood vessels in malignant tissue.
2). Impacting the tumor directly and destroying the malignant cells.
3). Reducing the malignant cell division, thus slowing tumor growth.
4). Reducing possibility of metastasis./Reducing possibility of disease recurrence
5).Speeding up post-surgery recovery / Improving the patient’s quality of life / Reducing pain

Pharmaceutical Researches and Studies on Ganoderma Lucidum Spore Powder
Ganoderma spores inhibit the growth of human bladder cancer cells
Jian Yu Rao and colleagues at the Department Pathology and Laboratory Medicine, University of California, Los Angeles, USA (2004) conducted experiments which revealed that preparations of Ganoderma spores can inhibit the growth of human bladder cells. By studying the effects of the preparations on actin proteins, they showed that Ganderma causes the proteins to polymerize excessively, leading to a blockage in the cell division.(http://reishi.setamed.com/articulos/art21.pdf) 

Ganoderma spores inhibit the growth of blood vessels supplying human prostate cancer cells 
Daniel Sliva and colleagues at the Cancer Research Laboratory and Department of Medicine, University of Indiana, USA (2005) showed that preparations of Ganoderma spores can inhibit the growth of the blood vessels that supply human prostate cancer cells with oxygen and nutrients, causing the prostate cancer to die. They also produced data which suggests that Ganoderma directly blocks secretions from the growth that help the prostate cancer cells to divide. (http://boliviapuertapuerta.com/img/DXN/art11.pdf)

Ganoderma spores cause rounding and death of human breast cancer cells 
Burton B. Yang and colleagues at the Department of Laboratory Medicine and Pathology, University of Toronto, Canada (2005) showed that preparations of Ganoderma spores reduce the numbers of integrin proteins at the surfaces of malignant human breast cancer cells. These proteins cause cells to adhere. But when exposed to Ganoderma spores, the breast cancer cells used by the team separated and died. 

Ganoderma spores inhibit growth of vascular cells that carry blood to lung cancer cells
Qu-zehn Cao and Zhi-Bin Lin at the Peking University of Health Science and the Department of Pharmacology at Peking University, China(2005) showed that polysaccarides in Ganoderma spores inhibit the growth of the vascular cells that carry blood to human lung cancers cells. In doing this Ganoderma spores help to starve cancer cells of oxygen and nutrients, causing them to die. (http://reishi.setamed.com/articulos/art9.pdf)

Ganoderma spores cause human breast cancer cells to die
Burton B. Yang and colleagues at the Department of Laboratory Medicine and Pathology, University of Toronto, Canada (2006) showed that preparations of Ganoderma spores cause malignant human breast cancer cells growing in culture dishes to separate from the dishes, round up and die. They discovered that the spores collected from Ganoderma grown on wood logs were most effective. 

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