Tongkat Ali Extract

【Latin name】: Eurycoma longifolia jack
【Active Ingredients】: Guassinoids,Eurycomanone, Eurycomanol, Eurycomalactone; Various Canthine-6-one Alkaloids
【Plant part used】: Root
【Specification】:100:1, 200:1
【Testing methods】: TLC
【Appearance】: Light yellow fine powder
【Particle size】: 100% pass 80 mesh
【Solubility】: Soluble in water
【Extract Method】: Hot aqueous/water extract
【Main Function】: Maintain testosterone level


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Brief Introduction of Tonkat ali
Tongkat Ali is a tree native to the jungles of Malaysia, Thailand, and Indonesia. It is commonly known as tongkat ali in Malaysia and Singapore, Tung Saw inThailand, and Pasak Bumi in Indonesia. Natives consider every part of the tree as medicine. The root has been used as traditional medicine and promoted as a tonic, energy enhancer, and as an aphrodisiac.

Tongkat Ali, Longjack, Eurycoma longifolia so known as Pasak Bumi, contains anti-oxidant properties, a high level of SOD (Superoxide Dismutase), an anti-oxidant enzyme. Research has shown that Eurycoma Longifolia Jack contains several phytochemicals (plant chemicals) that support healthy testosterone levels required for the male sexual functions. It also supports healthy sexual organs and mental alertness. Properly tongkat ali standardized hot-water extracts have a distinctly bitter taste due to the presence of quassinoids, which are recognized as some of the bitterest compounds in nature. Tongkat ali extracts that do not taste bitter are either not true Eurycoma longifolia root (there are many commercial examples of “fake” tongkat ali extracts) or are sub-potent in terms of bioactive constituents, and thus would also be expected to have low efficacy. Because of tongkat ali’s reputation for libido benefits, there are several examples of dietary supplements labeled as Eurycoma longifolia, but containing none of the actual tongkat root, and instead by adding prescription erectile dysfunction drugs including tadalafil/Cialis, sildenafil/ Viagra, and vardenafil/Levitra. These medicines are produced initially to treat erectile dysfunction, and will show a quick effect in erection but they all have a strong dependence property which will cause worse situation once a common people stop taking them.

Tongkat Ali as a Testosterone Level Maintainence
In both men and women, testosterone levels peak between 25 to 30 years of age – and thereafter drop approximately 1-2% annually. At the age of 60, testosterone levels are typically only 40-50% of youthful levels and may be lower due to stress and related lifestyle issues such as diet, exercise, and sleep patterns. The benefits of maintaining a youthful testosterone levels are many, including increased muscle mass and reduced body fat, high psychological vigor (mental/physical energy), and improved general well-being. Let’s have a look of the risks we may face with a low testosterone level in body:

Risks of low Testosterone
1) Osteoporosis and hip fracture
2) Heart disease and myocardial infarction
3) Stroke and cardiovascular disease
4) Prostate cancer
5) Senile dementia

And the benefits of testosterone in a normal level 
1) Stronger bones
2) Increase muscle mass
3) Decrease body fat
4) Increase metabolic rates and oxidative phosphorylation
5) Decrease stress
6) Improve brain function including memory
7) Improve sexual performance

Eurycoma contains a group of small peptides referred to as “eurypeptides” that are known to have effects in improving energy status and sex drive in studies of rodents (Asiah O, Nurhanan MY, Ilham MA: Determination of bioactive peptide (4.3kDa) as an aphrodisiac marker in six Malaysia plants. Journal of TropicalForest Science 2007, 19(1):61–63. )The effects of tongkat ali in restoring normal testosterone levels appears to be less due to actually “stimulating” testosterone synthesis, but rather by increasing the release rate of “free” testosterone from its binding hormone, sex-hormone-binding-globulin (SHBG)(Tambi MI: Water soluble extract of Eurycoma longifolia in enhancing testosterone in males. In Proceedings of the SupplySide West International Trade Show and Conference. Virgo Publishing; 2003. Oct 1–3.). In this way, eurycoma may be considered not so much a testosterone “booster” like the role anabolic steroid plays, but rather a “maintainer” of normal testosterone levels and a “restorer” of normal testosterone levels (from “low” back “up” to normal ranges). This would make eurycoma particularly beneficial for individuals with sub-normal testosterone levels, including those who are dieting for weight loss, middle-aged individuals suffering with fatigue or depression, and intensely training athletes who may be at risk for overtraining.

How Does Tongkat Ali Extract Work?
Tongkat Ali contains the effective ingredient that works by blocking the negative feedback cycle that occurs when your testosterone level reaches its natural peak, as your natural peak is reached without Tongkat your body sends a signal to the pituitary gland and hypothalamus that initiates a decrease in testosterone production. The Tongkat Ali blocks this signal allowing your body to produce testosterone at a steadily increasing rate well above your natural level, this steady increase of free testosterone in the body has been clinically proven to increase strength, increase muscle mass, reduce body fat and increase sex drive.

With Tongkat Ali You will experience
*Strong and prolonged erections
*Promoted sexuality
*Improved orgasm
*Increased vitality
Week (1).  During your first week you will not notice an obvious/huge change in your body since an increased sex drive should be noticeable when the testosterone level will be just over normal which will take some time to recover.
Week (2).  By week two you may notice a steady increase in strength and a faster recovery rate after training.
Week (3). During week three you should experience your strength increasing further as well as a heightened sense of well-being, you may also notice a slight increase in aggressiveness towards your workout and a slightly shorter temper than normal this is just a side effect from the extra testosterone in your body. If at any time you find it hard to control your aggression stop taking the Tongkat ali until you feel you are ready to continue the cycle.
Week (4). By now you should have noticed an increase in lean muscle mass as well as a noticeable reduction of body fat also your general feel good factor and confidence levels should be significantly higher than normal.
Week (5) & (6). During weeks five and six your testosterone levels will be substantially higher than normal, and you will notice the greatest benefits from the products getting gains of lean muscle mass and depending on your initial BMI you should see further reductions in body fat.

Modern Researches
1).Tongkat Ali aphrodisiac study review
Over the past few years, there have been quite a number of studies (particularly in rodents) that have tested it in relation to sexual effects. The results have been quite positive. There is some evidence that the use of this herb, at least in high dosages in rodents, increases levels of testosterone.

A randomized, double-blind, placebo controlled, parallel group study was carried out to investigate the clinical evidence of tongkat ali in men. The 12-week study in 109 men between 30 and 55 years of age consisted of either treatment of 300mg of water extract of tongkat ali (Physta) or placebo. Primary endpoints were the Quality of Life questionnaire and Sexual Well-Being investigated by International Index of Erectile Function and Sexual Health Questionnaires ; Seminal Fluid Analysis (SFA), fat mass and safety profiles. The tongkat ali group showed higher scores in sexual l-ibido and better s-perm motility and semen volume. Subjects with BMI ≥ 25kg/m significantly improved in fat mass loss. All safety parameters were comparable to placebo.(Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of Eurycoma longifolia for the Improvement of Quality of Life and Sexual Well-Being in Men. Evidence Based Complement Alternative Med. 2012. School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Kubang Kerian,Malaysia.)

The effects of this aphrodisiac herb were studied on libido of male rats after dosing them twice daily for 10 days. Tongkat ali produced a dose-dependent increase in mounting frequency; that is, the number of times the male rats tried to mount the female rats increased as the dose given to the rats increased. In addition, the rats displayed more frequent and vigorous licking and anogenital sniffing towards the receptive females. Furthermore, the rats dosed with the plant extract spent more time grooming their genitals compared to the rats who were not given the plant. Genital grooming may be interpreted as self-pleasuring since the rats were most likely enjoying the sensation of touching themselves. The researchers noticed another interesting finding: while the rats who had not received tongkat ali showed normal behavior within the cage such as exploration and climbing the cage wall, the rats given tongkat ali hung around the females instead of exploring the cage. In terms of human species, this may be interpreted as a man spending more time in the kitchen helping his wife dry the dishes than in the den half-asleep in a Lazyboy chair with the remote control in the left hand and a can of beer in the right while tuned to ESPN.

In this study we evaluated the influence of Eurycoma longifolia on sexual behavior (including both motivation and copulatory performance) of sexually sluggish and impotent male rats. Treatment with the root powder significantly reduced ejaculation latencies, increasing also the percentage of mounting and ejaculating animals. In impotent rats treatments increased the percentage of mounting and ejaculating rats. Testosterone serum levels were increased in rats treated in comparison with controls. (Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats.J Ethnopharmacol. 2009. Department of Biomedical Sciences, Section of Pharmacology, University of Modena and Reggio Emilia, ModenaItaly).

2).Mechanism of action 
More studies are required to determine the exact mechanisms of action. Recent studies indicate that the root contains several compounds including beta-carboline alkaloids and quassinoid-type glycosides, including eurycomaoside. How these compounds and many others in tongkat ali influence hormonal release or the human sexual response is not clearly understood at this time. Apparently some human trials have been conducted in Malaysia that indicate tongkat ali influences testosterone and this herb in has shown to raise testosterone levels in rodent studies. The plant parts have many compounds (such as eurycomaoside, eurycolactone, eurycomalactone, eurycomanone, and pasakbumin-B) among which the alkaloids and quassinoids form a major portion.

Considering that human studies are not available, 76 of 320 patients suffering from late-onset hypogonadism (LOH) were given 200 mg of a standardized water-soluble extract of Tongkat ali for one month. The Ageing Males’ Symptoms (AMS) according to the standardized rating scale and the serum testosterone concentration were taken. Results show that treatment of LOH patients with this Tongkat ali extract significantly improved the AMS score as well as the serum testosterone concentration. While before treatment only 10% of the patients did not show any complaint according to the AMS scale and 35% had normal testosterone levels, after the completed treatment 71% and 90% of the patients showed normal values, respectively. Thus, Tongkat ali extract appears to be useful as a supplement in overcoming the symptoms of LOH and for the management of hypogonadism.(Department of Community Medicine,School of Medical Sciences, Universiti Sains Malaysia, Kbg Kerian, Kelantan, Malaysia.Andrologia. 2011. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as t-estosterone booster for managing men with late-onset hypogonadism? Wellmen Clinic, Damai Service Hospital, Kuala Lumpur,Malaysia;)

We examined the effect of 9-hydroxycanthin-6-one (9-HC-6-one), a β-carboline alkaloid isolated from E. longifolia, on p-enile erection and e-jaculation, and further elucidated the mechanism of action. Results show 9-HC-6-one might be the active component that contributed to the a-phrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of c-orpus cavernosum through interfering with Ca2+ mobilization.(J Sex Med. 2012. 13.9-hydroxycanthin-6-one induces p-enile erection and delays ejaculation. National Research Institute of Chinese Medicine, Taipei, Taiwan.)

A water extraction method has been used to extract plant proteins from the roots of tongkat ali harvested from Perak and Pahang, Malaysia. On the basis of the spectroscopic Bradford assay, Tongkat Ali Perak and Pahang contained 0.38 and 0.95mg mL(-1) of crude protein, respectively. Isoleucine was present in the highest concentration. Both plant samples showed differences in the mineral and trace element profiles, but the minerals calcium, magnesium and potassium were present in the highest concentration. The highly concerned toxic metals such as arsenic and lead were not detected.(Nat Prod Res. 2013. Plant proteins, minerals and trace elements of Eurycoma longifolia (Tongkat Ali). Metabolites Profiling Laboratory, Institute of Bioproduct Development, Universiti Teknologi Malaysia, UTM Skudai, Johor, Malaysia.)

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One Response to Tongkat Ali Extract
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