Aconite (Fu Zi) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Fu Zi, Radix Aconiti Lateralis Praeparata, Fu Pian, Shu Fu, monkshood, radix aconiti carmichaeli
【Botanical source】: Aconitum carmichaelii Debx
【Part used】: Processed product of the sub roots of Aconitum carmichaelii Debx, a plant in the Ranunculaceae family. Excavate from late June to early August, remove the mother roots, fibrous roots, and sediment, commonly known as “mud aconite”, clean and sun dry slices.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Aconite (Fu Zi) Extract Powder Production Flowchart
Aconite (Fu Zi) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Aconite (Fu Zi) Extract Powder

Extended Reading
Aconite (Fu Zi) Function and Efficacy Recorded in TCM
Fuzi is an extremely important and distinctive medicine in traditional Chinese medicine. It is known as the “first grade medicine for returning yang and rescuing reverse”, but at the same time, it needs to be used with caution due to its “great toxicity”. Fuzi is a processed product of the lateral root of Aconitum, a plant in the Ranunculaceae family. Medicinal properties: Da Xin, Da Re; Toxic. Returning to the Heart, Kidney, and Spleen Meridians. Core function: Returning yang and relieving reverse, replenishing fire and assisting yang, dispersing cold and relieving pain.

Simply put, Fuzi is an extremely powerful medicine that can invigorate the dying yang energy in the human body and dispel the cold pathogens that penetrate deep into the bone marrow. It is a “great general” used to treat critical illnesses.

1. Returning to Yang to save the rebellion
This is the most essential and irreplaceable role of Fuzi. Used for treating ‘Yang deficiency syndrome’.

What is the Yang deficiency syndrome? This is the most dangerous deficiency cold syndrome, characterized by extreme decline of yang qi and imminent cessation of vital functions.

Symptoms: Cold sweat, cold limbs (cold to the elbows and knees), weak pulse, weak breathing, and confusion.

Application: In modern medicine, it is equivalent to critical situations such as shock, heart failure, and circulatory failure caused by various reasons. Fuzi can instantly invigorate the body’s yang energy, turn the tide, and pull life back from the brink of death.

Classic formula: Sini Tang (Fuzi, dried ginger, licorice), is the basic formula for returning yang and rescuing reverse.

2. Nourish fire and promote yang
Fuzi can warm and replenish the body’s yang energy, and it can play a powerful role in adding firewood and fire to any illness caused by insufficient yang energy.

Kidney Yang Deficiency: This is the main battlefield of Fuzi. Symptoms include cold pain in the waist and knees, chills in the limbs, frequent nocturia, erectile dysfunction and premature ejaculation, and infertility caused by uterine coldness. It is the first powerful medicine for tonifying kidney yang. Classic formulas such as Kidney Qi Pill and Right Return Pill.

Spleen Yang Deficiency: manifested as cold pain in the epigastric region, loose stools, and complete non melting (with undigested food in the stool). Fuzi can warm the spleen and soil, enhance the function of transportation and metabolism.

Heart yang deficiency: manifested as palpitations, chest pain, chest tightness, shortness of breath, and warm hands and feet. Fuzi can strengthen the heart and unblock the meridians.

Wei Yang deficiency: manifested as a special fear of wind, susceptibility to colds, and spontaneous sweating (not sweating due to activity). Fuzi can strengthen the protective surface, such as the formula Ma Huang Fuzi Xi Xin Tang.

3. Relieve cold and relieve pain
Fuzi is pungent, hot, and dry, which can warm and unblock meridians, expel wind, cold, and dampness evil between meridians, tendons, and bones, and has a strong analgesic effect.

Used for wind cold dampness obstruction: especially suitable for “pain obstruction” caused by excessive cold pathogenic factors, manifested as joint and muscle cold pain, severe pain, aggravated by cold, and relieved by heat. It is effective for stubborn pain such as rheumatoid arthritis and sciatica.

Used for invasion of cold pathogens: such as cold hernia and abdominal pain (cold pain caused by small intestinal hernia).

Modern Pharmacological Effects of Aconite (Fu Zi)
The modern pharmacological research on Fuzi is very in-depth, which not only confirms the scientific validity of its traditional efficacy, but also reveals the mechanism of its toxicity and provides guidance for safe medication.

The pharmacological effects of Aconitum are closely related to its toxicity, and its active and toxic components are highly overlapping, mainly composed of aconitine alkaloids (such as aconitine, aconitine, and aconitine). The processing and decoction process of “reducing toxicity and preserving efficacy” or “reducing toxicity and enhancing efficacy” refers to the conversion of these diester alkaloids into less toxic but still active monoester or amine alcohol alkaloids.

1. Cardiotonic, anti shock, and cardiovascular system effects
This is a modern scientific interpretation of its “returning yang and rescuing rebellion” effect.

Cardiotonic effect: Aconitum can significantly enhance myocardial contractility and increase cardiac output. Its mechanism of action is complex, including excitation of β – adrenergic receptors, promotion of endogenous catecholamine release, inhibition of myocardial cell membrane Na ⁺ – K ⁺ – ATPase, etc.

Anti shock: It has therapeutic effects on shock caused by various reasons (such as cardiogenic shock and hemorrhagic shock), can raise blood pressure, improve microcirculation, which is related to its cardiotonic and vasodilatory effects.

Bidirectional regulation of heart rhythm:
Toxic dose: High concentrations of aconitine can extremely excite the myocardium, leading to arrhythmia such as premature ventricular contractions, ventricular tachycardia, ventricular fibrillation, etc. This is the main cause of its poisoning death.

Therapeutic dose: After reasonable processing and decoction, Fuzi and its compound (such as Shenfu injection) have therapeutic effects on certain slow arrhythmias, can increase heart rate, and improve atrioventricular conduction.

2. Anti inflammatory and analgesic effects
This corresponds to its effectiveness in dispelling cold and relieving pain, especially in the treatment of wind cold dampness syndrome (such as rheumatoid arthritis).

Anti inflammatory: Aconitum can significantly inhibit various acute and chronic inflammation models, and its mechanism is related to the inhibition of the production and release of inflammatory mediators such as prostaglandins and histamine.

Analgesia: It has a significant analgesic effect on both the central and peripheral nervous systems, and its analgesic efficacy is strong.

3. Effects on the immune system
Immune enhancement: Aconitum can stimulate the immune system, promote antibody production, increase lymphocyte transformation rate, and enhance the phagocytic function of macrophages. This explains part of the mechanism by which it can “assist the righteous qi” in treating Yang deficiency syndrome.

Immune regulation: Under certain conditions, it also exhibits anti allergic effects.

4. Resistance to cold and improvement of hypoxia tolerance
Cold resistant: Aconitum can improve the survival rate of animals in low temperature environments and delay the decrease in body temperature. This is directly related to its effect of “tonifying fire and aiding yang” and improving the body’s metabolism and heat production.

Hypoxia tolerance: It can improve the body’s ability to tolerate hypoxia and protect important organs such as the heart and brain.

5. Effects on the nervous system
Excitatory effect: It has a first excitatory and then paralyzing effect on the central and peripheral nerves. Low doses can stimulate the sympathetic nervous system, which is also one of its mechanisms for strengthening the heart and dispelling coldness.

Local anesthesia: Aconitine itself has a local anesthetic effect of first exciting and then paralyzing nerve endings, but due to its strong systemic toxicity, it is generally not used for clinical anesthesia.