Belamcanda (She Gan) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: She Gan, Rhizoma Belamcandae, Blackberrykiky Rhizome
【Botanical source】: Belamcanda chinensis（L.）DC.
【Part used】: The dried rhizomes of Belamcanda chinensis (L.) DC, a plant in the Iridaceae family. At the beginning of spring when the plant has just sprouted or at the end of autumn when the stems and leaves wither, dig and remove the roots and sediment, and dry it.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Belamcanda (She Gan) Extract Powder Production Flowchart
Belamcanda (She Gan) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Belamcanda (She Gan) Extract Powder

Extended Reading
Belamcanda (She Gan) Function and Efficacy Recorded in TCM
In traditional Chinese medicine theory, Belamcanda (She Gan) has a bitter and cold nature, and belongs to the lung meridian. Its core function is to “clear heat and detoxify, eliminate phlegm and clear throat”. It is particularly famous for treating sore throat and is an essential medicine in the field of laryngology. The following is a detailed breakdown of its specific function:

1. Clearing heat, detoxifying, and relieving pain (core function)

This is the most prominent and commonly used effect of shooting stems.

Regarding the symptoms:
Throat swelling and pain caused by heat toxin phlegm fire stagnation. This type of sore throat is usually very severe, with difficulty swallowing and even accompanied by hoarseness.

Acute tonsillitis, acute pharyngitis, and laryngitis.

Mechanism: Shooting dry, bitter cold, clearing and releasing fluids can directly break up the fire poison and phlegm heat attacking the throat, thereby quickly reducing swelling and relieving pain. The famous traditional Chinese patent medicines and simple preparations “Houzhen Pill” contains Shegan.

2. Eliminate phlegm and disperse nodules

Regarding the symptoms:
Excessive phlegm and saliva, coughing and wheezing. It has a good effect on phlegm accumulation, coughing and wheezing, and the sound of phlegm in the throat (referred to as “chicken voice in the throat” in traditional Chinese medicine).

Commonly used to treat conditions such as asthma, bronchitis, and phlegm heat obstructing the lungs.

Mechanism: Belamcanda (She Gan) can not only clear lung heat, but also reduce retrograde qi, eliminate stubborn phlegm, and make the airway unobstructed, which can calm cough and asthma.|

3. Disperse blood and reduce swelling
This is a secondary but related role. Its nature is cold and enters the bloodstream, which can dissipate the abscess and ulcer caused by heat toxicity and stasis.

Modern Pharmacological Effects of Belamcanda (She Gan)
The main active ingredients of Belamcanda (She Gan) include flavonoids (such as irisin, irisin, and irisin), triterpenoids, phenolic acids, and so on. The following are the main modern pharmacological effects of Belamcanda (She Gan) that have been confirmed:

1. Anti inflammatory effect
This is one of the core pharmacological effects of Belamcanda (She Gan), which directly corresponds to its effects of clearing heat, detoxifying, and reducing swelling.

Mechanism: Flavonoids in Shegan (especially irisin) can significantly inhibit the production of various key inflammatory mediators, such as:
Tumor necrosis factor alpha (TNF – α)
Interleukin-6 (IL-6)
Prostaglandin E2 (PGE2)
Nitric oxide (NO)

Application: This is the fundamental pharmacological basis for its treatment of inflammatory diseases such as pharyngitis, tonsillitis, bronchitis, etc.

2. Antibacterial and antiviral effects
Antibacterial: Belamcanda (She Gan) extract has inhibitory effects on various common clinical pathogenic bacteria, including:

Gram positive bacteria: such as Staphylococcus aureus and Streptococcus pyogenes (which are the main bacteria causing pharyngitis).

Gram negative bacteria: such as Escherichia coli, Pseudomonas aeruginosa, etc.

Antiviral: Studies have shown that Belamcanda (She Gan) has significant inhibitory effects on influenza virus, respiratory syncytial virus (RSV), herpes virus (HSV), and coxsackievirus.

Application: This provides a scientific basis for its treatment of bacterial and viral upper respiratory tract infections.

3. expectorant and anti asthmatic effects
Phlegm removal: Belamcanda (She Gan) can promote the secretion of respiratory glands, dilute phlegm, and make it easier to cough up. This is related to the saponin components contained in it.

Relieve asthma: The ingredients in Belamcanda (She Gan) can counteract the contraction of tracheal smooth muscle caused by histamine, and have the effect of relieving spasms and asthma.

Application: This directly confirms its traditional efficacy of “eliminating phlegm and dispersing nodules” and treating cough and asthma.

4. Antipyretic and analgesic effects
Antipyretic: Belamcanda (She Gan) has a good antipyretic effect on fever caused by bacterial endotoxins and other factors.

Analgesia: It can significantly inhibit pain responses caused by chemical and thermal stimuli.

Application: This explains its role in treating sore throat (pain relief) and infectious fever (fever reduction).

5. Immune regulatory effect
Belamcanda (She Gan) has a bidirectional regulatory effect on the immune system.

In inflammatory and infectious states, it can suppress excessive immune responses through anti-inflammatory effects.

At the same time, it can also enhance the phagocytic function of macrophages to a certain extent, helping the body eliminate pathogens.

6. Antitumor effect
This is currently a hot research topic.

Mechanism: The active ingredients in Belamcanda (She Gan) (such as irisin) have shown in vitro and animal experiments that:

Inhibit tumor cell proliferation (such as liver cancer, lung cancer, and gastric cancer cells).
Inducing apoptosis of tumor cells.
Inhibit tumor angiogenesis.
Current situation: This effect is currently mostly in the preclinical research stage, but it has shown potential application prospects.

7. Antioxidant effect
The flavonoids in Belamcanda (She Gan) are natural antioxidants that can effectively eliminate free radicals and reduce oxidative stress damage to body tissues such as lung tissue.