Burdock Seed (Niu Bang Zi) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Niu Bang Zi, Fructus Arctii, Shu Nian Zi, Great Burdock Achene, Arctii Fructus, Burdock seed
【Botanical source】: Arctium lappa L.
【Part used】: Dried ripe fruit of Arctium lappa L, a plant in the Asteraceae family. When the autumn fruits are ripe, harvest them in sequence, dry them in the sun, seed the fruits, remove impurities, and then dry them in the sun.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Burdock Seed (Niu Bang Zi) Extract Powder Production Flowchart
Burdock Seed (Niu Bang Zi) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing
Specification Sheet of Burdock Seed (Niu Bang Zi) Extract Powder

Extended Reading
Burdock Seed (Niu Bang Zi) Function and Efficacy Recorded in TCM
Burdock seed is a commonly used heat clearing and detoxifying medicine in traditional Chinese medicine, derived from the dried and ripe fruit of the burdock plant. Its nature is pungent, bitter, and cold, and it belongs to the lung and stomach meridians.

Its core function can be summarized as “dispelling wind and heat, detoxifying and benefiting the throat”, especially adept at treating diseases related to “wind heat”. The following are its specific functions and clinical applications:

1.Evacuate wind and heat, promote lung rash
Mechanism of action: Burdock seed has the properties of being pungent, bitter, and cold clearing. It can disperse the wind and heat evil qi in the lung meridian, allowing the evil qi to dissipate from the surface. At the same time, it has a penetrative effect on rashes.

Indicative symptoms:
Wind heat cold, at the beginning of warm disease: For cold symptoms such as severe fever, slight evil wind, sore throat, cough and phlegm, it is often combined with honeysuckle, forsythia suspensa, mint, etc., such as the famous formula “Yinqiao Powder”.

Measles not transparent: When measles cannot penetrate smoothly due to wind and heat, burdock seeds can be used to help the virus penetrate outward, often used in the same way as peppermint, tamarisk, and bamboo leaves.

2. Clearing heat and detoxifying, promoting throat and reducing swelling
Mechanism of action: This is the most prominent and commonly used efficacy of burdock seeds. It is bitter, cold, and can relieve heat toxins in the lungs and stomach, especially good at clearing the throat.

Indicative symptoms:
Throat swelling and pain: Whether it is caused by wind heat and cold, or by excessive heat in the lungs and stomach, or by the invasion of fire and toxins, throat swelling and pain, tonsillitis, burdock seeds are all necessary medicine. Often combined with mint, bellflower, licorice, Isatis root, mountain bean root, etc.

Pimpless (mumps): often used together with heat clearing and detoxifying drugs such as Huanglian, Huangqin, and Banlangen, such as “Puji Disinfection Drink”.

Dandelion, abscess and ulcer toxin: can be used to treat skin infections caused by heat toxicity, often combined with honeysuckle, forsythia suspensa, wild chrysanthemum, etc.

3. Relieve constipation
Mechanism of action: Burdock seeds are rich in oil and fat, with a smooth texture and the ability to smooth the intestines and promote bowel movements.

Clinical application: This characteristic has duality in treatment:
Advantage: It is particularly suitable for patients with wind heat or lung heat stagnation, accompanied by constipation. Because traditional Chinese medicine believes that “the lungs and the large intestine are on the surface and inside”, passing stool can help eliminate lung heat and have a “radical effect”, which is beneficial for clearing heat toxins in the throat and lungs.

Attention: It is precisely because of this characteristic that people with spleen deficiency diarrhea and loose stools must use it with caution to avoid worsening the condition.

Modern Pharmacological Effects of Burdock Seed (Niu Bang Zi)
The main active ingredients of burdock seeds include lignans (such as burdock glycoside and burdock glycoside), volatile oils, fatty acids, alkaloids, polysaccharides, etc. Its pharmacological effects mainly revolve around these components. The following are the main modern pharmacological effects of burdock seeds:

1. Anti inflammatory and analgesic effects
Mechanism of action: Studies have shown that extracts of burdock seeds and their main component, burdock glycoside, can significantly inhibit the production and release of various inflammatory factors (such as TNF – α, IL-6, IL-1 β), and exert strong anti-inflammatory effects by regulating inflammatory signaling pathways such as NF – κ B.

Related applications: This directly confirms its traditional efficacy in treating “heat toxicity” diseases such as sore throat and mumps.

2. Antibacterial and antiviral effects
Antibacterial: Extracts from burdock seeds have inhibitory effects on various Gram positive and Gram negative bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae.

Antiviral: This is an important manifestation of its “dispersing wind and heat” effect. Burdock has certain inhibitory activity against influenza virus, parainfluenza virus, respiratory syncytial virus, even human immunodeficiency virus (HIV) and SARS virus. The mechanism may be related to preventing the virus from adsorbing host cells and inhibiting virus replication.

3. Antitumor effect
Mechanism of action: This is currently a hot research topic. Arctiin and its aglycones have been shown to inhibit tumor cell proliferation, induce tumor cell apoptosis (programmed cell death), inhibit tumor angiogenesis, and reverse multidrug resistance of tumor cells through multiple pathways.

Research scope: In vitro and animal experiments, it has shown its inhibitory effect on lung cancer, liver cancer, stomach cancer, colon cancer, breast cancer and other cancer cell lines.

4. Reducing blood sugar and improving complications of diabetes
Mechanism of action: Various components in burdock seeds, such as burdock glycoside and polysaccharides, have significant hypoglycemic activity.

The mechanism includes:
Improve insulin sensitivity.
Protect pancreatic beta cells.
Inhibit the absorption of sugar in the intestine.
Improve insulin resistance.

Related applications: In addition, it can also reduce the common complications of diabetes, such as kidney, retina and neuropathy, and has broad development prospects.

5. Immune regulatory effect
Polysaccharides from burdock root can enhance the phagocytic function of macrophages, promote lymphocyte proliferation, regulate cytokine secretion, and thus enhance the non-specific and specific immune (including humoral and cellular immune) functions of the body. This is consistent with the concept of “strengthening the body and eliminating evil” in traditional Chinese medicine.

6. Neuroprotective effect
Research has found that arctigenin has a protective effect on nerve cells and may have potential therapeutic value for neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. The mechanism may be related to antioxidant activity, inhibition of β – amyloid deposition, and excessive phosphorylation of Tau protein.

7. Antioxidant effect
The phenolic acids and lignans in burdock seeds have strong ability to scavenge free radicals such as DPPH and ABTS, which can alleviate the damage of oxidative stress to body tissues. This is closely related to its anti-aging, anti-inflammatory, and anti-tumor effects.

8. Effects on the cardiovascular system
Arctium lappa extract showed the potential of lowering blood pressure, blood lipid and anti atherosclerosis. It can help dilate blood vessels and reduce total cholesterol and triglyceride levels.

9. Moisturizing and laxative effects
Burdock seeds are rich in oil (about 25% -30%), and the fatty acids they contain can lubricate the intestines. Meanwhile, arctiin has a slight irritant effect and can promote intestinal peristalsis, thereby playing a role in relieving diarrhea and promoting bowel movements.