Cinnamon (Rou Gui) Extract Powder 10:1, 20:1, 50:1 TLC

Cinnamon (Rou Gui) Extract Powder 10:1, 20:1, 50:1 TLC

The functions of cinnamon in traditional Chinese medicine include tonifying fire and promoting yang, inducing fire to return to the original energy, dispelling cold and relieving pain, and warming the meridians. Used for impotence, uterine coldness, lower back and knee pain, wheezing due to kidney deficiency, floating yang due to deficiency, dizziness, red eyes, cold and abdominal pain, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea and amenorrhea.

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Cinnamon (Rou Gui) Extract Powder 10:1, 20:1, 50:1 TLC
Other names: Rou Gui, Cortex Cinnamomi, Gui Xin,Guan Gui, Cinnamon Bark
Botanical source: Cinnamomum cassia Presl
Part used: Dry bark of Cinnamomum cassia Presl. Cinnamon is in the shape of grooves or rolls, measuring 30-40 cm in length, 3-10 cm in width or diameter, and 0.2-0.8 cm in thickness. The outer surface is gray brown, slightly rough, with irregular fine wrinkles and horizontally protruding skin holes, and some have visible gray white spots; The inner surface is reddish brown, slightly flat, with fine longitudinal lines and visible oil marks when scratched. Hard and brittle in texture, easy to break, with an uneven cross-section. The outer layer is brown and rough, while the inner layer is reddish brown and oily. There is a yellow brown line between the two layers. Strong aroma, sweet and spicy taste.
Specification: 10:1, 20:1, 50:1 TLC
Appearance: Brownish yellow fine powder
Particle size: 95% pass 80 mesh size
Cinnamon (Rou Gui) Extract Powder Production Flowchart
Cinnamon (Rou Gui) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1st Reflux Extraction(10 times water,2 Hrs) – 2nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Cinnamon (Rou Gui) Extract Powder

Product name: Rou Gui Extract
Specification: 10:1 TLC
Part used: Dried roots of Cinnamomum cassia Presl
Solvent used: Hot water
Process: Raw materials crushed, extracted, concentrated and spray-dried to powder
Non GMO according to regulation (EC) 1829/2003 and 1830/2003 or United States requirements. Non allergen according to Directive 2007/68 amending Annex IIIa to Directive 2000/13/EC and US Food allergen labelling and consumer protection act 2004.
Heavy Metals:
Lead: NMT 3ppm Cadmium: NMT 1ppm
Arsenic: NMT 2ppm Mercury: NMT 1ppm
Residual solvents: Comply to USP
Pesticides residues: Conform to Regulation USP<561>
Microbiology:
Total plate count: 10000cfu/g Max Yeasts and molds: 1000cfu/g Max
E.coli: Not detected in (g)10 Salmonella spp.: Not detected in (g)25
Staphylococcus aureus: Not detected in (g)10 Clostridium spp.: Not Present in 0.1 g of food
Organoleptic quality Method Specifications
Aspect: Visual : ( CQ-MO-148) Powder
Color: Visual : ( CQ-MO-148) Brownish
Flavor: Sensory: (CQ-MO-148) Characteristic
Analytical quality Method Specifications
Identification: TLC Conform
Loss on drying: USP <731> < 10%
Bulk density: USP <616> Method I 40 – 60 g/100mL
Particle size: Analytical sieving || USP <786> 100% through 80meshes
Packaging suitable for foodstuff.

Extended Reading
Cinnamon (Rou Gui) Function and Efficacy Recorded in TCM
Cinnamon is the dried bark of the camphor plant cinnamon, which is a very important and commonly used warming medicine in traditional Chinese medicine. It has a strong odor, a sweet and spicy taste, a hot nature, and belongs to the kidney, spleen, heart, and liver meridians.

Its core function can be highly summarized as “tonifying fire and assisting yang, inducing fire to return to its original state, dispelling cold and relieving pain, warming and promoting meridians”. It is a powerful “warming yang” medicine.

1. Nourish fire and promote yang
Mechanism of action: Cinnamon has a strong heat and can warm and replenish the fire of the vital energy gate (i.e. kidney yang), making it one of the preferred drugs for treating kidney yang deficiency (kidney yang deficiency). Kidney yang is the fundamental source of yang energy in the human body, like the ‘sun’ of the body.

Indicative symptoms:
Kidney yang deficiency and decline: manifested as chills and cold limbs, cold and painful waist and knees, frequent nocturia, impotence and uterine coldness. Often combined with Fuzi, Rehmannia glutinosa, Cornus officinalis, etc., such as the famous formula “Kidney Qi Pill” or “Right Returning Drink”.

Spleen and kidney yang deficiency: When kidney yang cannot warm the spleen and soil, there may be diarrhea due to insufficient food intake and incomplete digestion (there is undigested food in the stool). Often used interchangeably with Fuzi, dried ginger, and Atractylodes macrocephala, such as “Guifu Lizhong Wan”.

2. Ignite and return to the original state
Mechanism of action: This is a very unique and exquisite effect of cinnamon. When the kidney yang deficiency reaches a certain degree, the weak yang qi will be rejected by the grid and float upwards, showing false heat symptoms of “upper heat and lower cold”, such as facial redness, toothache, sore throat, but at the same time, the lower limbs will be cold. Cinnamon can guide the floating virtual fire back to its original state (in the kidneys).

Indicative symptoms:
The above-mentioned false heat symptoms caused by the floating of deficiency yang. Often used in combination with Huanglian or added to a large amount of nourishing yin medicine.

3. Relieve cold and relieve pain
Mechanism of action: Cinnamon extract can dispel cold pathogens between muscles and bones, thereby relieving pain caused by the stagnation of cold pathogens.

Indicative symptoms:
Cold Bi Tong (the cold pathogenic factor in wind cold dampness Bi is more dominant): manifested as joint cold pain, aggravated by cold, and reduced when warm. Often used in combination with Duhuo, Mulberry Parasitic, Eucommia ulmoides, etc., such as “Duhuo Parasitic Soup”.

Chest obstruction and heartache: Chest pain and palpitations caused by invasion of cold pathogens, which can be used for angina pectoris in modern times. Often used interchangeably with aconite and dried ginger.

Cold hernia, abdominal pain, and dysmenorrhea in women (caused by cold).

4. Warm and smooth meridians
Mechanism of action: Cinnamon can warm and invigorate the blood vessels, promote blood circulation, and dispel blood vessel blockages caused by cold coagulation.

Indicative symptoms:
Yin Yang (such as bone tuberculosis, chronic deep abscess): manifested as diffuse swelling without head, unchanged skin color, and no or slight heat. It is often combined with cooked land, deer antler gum, ephedra, and other ingredients to form the famous “Yanghe Tang”. Cinnamon in this formula can warm and promote blood circulation, as well as facilitate the dissipation and absorption of pus.

Postpartum blood stasis and abdominal pain in women, as well as swelling and pain caused by bruises and injuries.

5. Warm up Yang Qi
Mechanism of action: Adding a small amount of cinnamon to the formula for tonifying qi and blood or nourishing yin can warm up yang qi, stimulate the growth of qi and blood, and make the tonic better absorbed and utilized without being greasy and hindering the stomach.

Application example:
Cinnamon is used in the “Ten Quan Da Bu Tang” (nourishing qi and blood).
Cinnamon is also used in the “Ginseng Nourishing Rongtang” to enhance its warming and promoting circulation of qi and blood.

Modern Pharmacological Effects of Cinnamon (Rou Gui)
The main active ingredients of cinnamon include volatile oil (mainly cinnamaldehyde), polyphenols (such as anthocyanins), flavonoids, polysaccharides, etc.The following are the main modern pharmacological effects of cinnamon:

1. Lowering blood sugar and improving insulin resistance
This is the most remarkable effect of cinnamon in modern pharmacological research.

Function: Numerous cellular, animal, and clinical studies have shown that cinnamon extract has significant hypoglycemic and insulin sensitivity enhancing effects.

Mechanism:
Imitation of insulin: Its components can activate insulin receptors and mimic the function of insulin.

Enhance insulin sensitivity: improve the cell’s ability to respond to insulin.

Promote glycogen synthesis: stimulate cells to take up glucose and convert it into glycogen storage.

Inhibition of intestinal sugar absorption: Inhibits the activity of enzymes related to sugar absorption, such as alpha glucosidase.

2. Effects on the cardiovascular system
Lower blood fat: Cinnamomum cassia can reduce the levels of serum total cholesterol, triglycerides and low-density lipoprotein (“bad” cholesterol), and has a preventive effect on atherosclerosis.

Lowering blood pressure: Its vasodilatory effect helps to lower blood pressure.

Antiplatelet aggregation: It can inhibit platelet aggregation and prevent thrombus formation, which confirms its traditional efficacy of promoting blood circulation and meridian circulation.

3. Antibacterial, antifungal, and antiviral properties
Function: Cinnamon volatile oil (especially cinnamaldehyde) has broad-spectrum and strong antibacterial and antifungal activity.

Target microorganisms:
Bacteria: Effective against various Gram positive and Gram negative bacteria, such as Staphylococcus aureus, Escherichia coli, Listeria monocytogenes, etc. This makes it a natural research object for food preservatives.

Fungi: have significant inhibitory effects on Candida albicans and other fungi.

Viruses: They also exhibit inhibitory potential against certain viruses such as influenza virus and HIV.

4. Anti inflammatory and antioxidant properties
Anti inflammatory: Polyphenols in cinnamon can inhibit inflammatory signaling pathways such as nuclear factor kappa B and reduce the production of inflammatory factors such as TNF – α and IL-6. This provides a basis for its treatment of inflammation related diseases.

Antioxidant: Cinnamon is one of the most potent spices known for its antioxidant activity, effectively clearing free radicals and reducing oxidative stress damage, which is related to anti-aging and prevention of chronic diseases.

5. Effects on the digestive system
Anti ulcer: Cinnamon can inhibit gastric acid secretion, increase gastric mucosal blood flow, and has a good preventive and therapeutic effect on experimental gastric ulcers.

Regulating gastrointestinal motility: It can not only inhibit gastrointestinal spasms, but also promote the secretion of digestive fluids and alleviate gastrointestinal bloating.

6. Neuroprotective effect
Research has shown that cinnamon extract and its components (such as cinnamaldehyde) have neuroprotective properties.

Potential benefits:
Inhibiting Tau protein aggregation and beta amyloid protein formation, both of which are biomarkers of Alzheimer’s disease.

Enhancing brain-derived neurotrophic factor may help improve symptoms of Parkinson’s disease and learning and memory abilities.

7.Antitumor effect
In vitro and animal experiments have shown that cinnamaldehyde and cinnamon extract have inhibitory effects on proliferation and induce apoptosis in various cancer cells, such as melanoma, leukemia, colorectal cancer, and gastric cancer cells. Its mechanism involves regulating multiple cellular signaling pathways.

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