Corydalis Yanhusuo (Yan Hu Suo) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Yan Hu Suo, Rhizoma Corydalis, Yuan Hu, Xuan Hu Suo
【Botanical source】: Corydalis yanhusuo W. T. Wang 
【Part used】: Dry tubers of Corydalis yanhusuo W. T. Wang plant. When the stems and leaves wither in early summer, dig them up, remove the roots, wash them, boil or steam them in boiling water until there is no white heart, take them out, and dry them in the sun
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Corydalis Yanhusuo (Yan Hu Suo) Extract Powder Production Flowchart
Corydalis Yanhusuo (Yan Hu Suo) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Corydalis Yanhusuo (Yan Hu Suo) Extract Powder

Extended Reading
Corydalis Yanhusuo (Yan Hu Suo) Function and Efficacy Recorded in TCM
Yanhusuo, also known as Yuanhu, enjoys a high reputation in traditional Chinese medicine and is known as the “first grade medicine for promoting blood circulation and qi circulation” and the “essential medicine for pain relief”. Its function is very specific and powerful, with the core being “pain relief”.

Core efficacy and mechanism of action

The core function of Corydalis yanhusuo is to promote blood circulation, promote qi circulation, and relieve pain. It has a warm nature, a spicy and bitter taste, and mainly belongs to the liver and spleen meridians. Traditional Chinese medicine believes that “if there is no connection, it will cause pain”. The occurrence of pain is due to the obstruction and stagnation of qi and blood in the body. Yanhusuo can not only enter the blood to promote blood circulation and remove blood stasis, but also enter the qi to dispel stagnation, thus cleverly solving the problem of “obstruction” and achieving the excellent effect of “general rule without pain”.

Its main functions can be summarized as follows:

1. Promote blood circulation, promote qi circulation, and relieve pain

This is the most fundamental and well-known efficacy of Corydalis yanhusuo.

Characteristics: The range of pain relief is very wide, covering various pains throughout the body. It can be considered for use in cases caused by stagnation of qi and blood. It is not like some painkillers that have a specific location bias (such as treating headaches or abdominal pain), but rather “versatile”.

Application:
Chest obstruction and heartache: Used for coronary heart disease and angina caused by qi stagnation and blood stasis, often combined with Danshen, Chuanxiong and other ingredients.

Stomach pain: Used for stomach pain caused by stagnation of qi and blood, it can be combined with Chuanzhenzi powder, also known as the famous Jinlingzi powder.

Rib pain: Used for rib distension caused by liver depression, qi stagnation, and blood stasis (such as intercostal neuralgia).

Dysmenorrhea, postpartum blood stasis and abdominal pain: Used for menstrual abdominal pain, amenorrhea, postpartum abdominal pain, etc. caused by blood stasis in women, often combined with Angelica sinensis, Puhuang, Chishao, etc.

Injury caused by falls and bruises, swelling and pain: Used for local bruising, swelling and pain caused by trauma, often used together with blood activating and healing medicines such as frankincense and myrrh.

Rheumatic rheumatism and rheumatism: Used for joint pain caused by wind cold dampness and rheumatism, it can be used together with wind dampness dispelling drugs such as cassia twig and gentian.

2. Functional characteristics
Strong pain relieving ability: Li Shizhen highly praised Yanhusuo in the “Compendium of Materia Medica”, stating that it “can treat stagnation of qi in the blood and stagnation of blood in the qi, so it is specifically used to treat various pains in the body, and its use is indescribable.

Peaceful medicinal properties: Compared to other blood activating drugs, the medicinal properties of Corydalis yanhusuo are relatively mild, promoting blood circulation without consuming too much blood.

Bi directional regulation: It can promote blood circulation and regulate qi, treating both qi and blood simultaneously. This is its unique advantage over many other painkillers.

Modern Pharmacological Effects of Corydalis Yanhusuo (Yan Hu Suo)
Modern pharmacological research not only fully confirms the traditional position of Corydalis yanhusuo as a “pain relieving medicine”, but also deeply reveals its material basis and specific mechanism of action. The main active ingredients of Corydalis yanhusuo are alkaloids, among which the analgesic effect of Corydalis yanhusuo ethyl (tetrahydropalmatine) is the most famous and powerful.

The following are the main modern pharmacological effects of Corydalis yanhusuo:

1. Analgesic effect
This is the most core and thoroughly studied pharmacological effect of Corydalis yanhusuo.

Active ingredients: mainly composed of berberine, in addition to berberine, berberine, etc.

Mechanism of action:
Yanhusuo Yi Su is not a traditional opioid analgesic. It mainly produces significant analgesic effects by blocking dopamine receptors and exerting extensive inhibitory effects on the central nervous system.

It can also affect the levels of other neurotransmitters in the brain, such as serotonin and norepinephrine, which jointly participate in analgesic regulation.

Features:
Wide range of pain relief: particularly effective for chronic persistent pain (such as headaches, menstrual cramps) and visceral spasmodic pain.

Non addictive: This is its significant advantage over opioid analgesics such as morphine. It does not bind to opioid receptors, so there is no risk of drug dependence and addiction.

Minor side effects: The side effects are mild at the therapeutic dose, commonly including sedation and drowsiness.

2. Sedative and hypnotic effects
Mechanism: Corydalis yanhusuo and its active ingredients have inhibitory effects on the cerebral cortex, subcortical structures, and brainstem.

Application: It has good sedative and hypnotic effects, can reduce spontaneous activity, enhance the hypnotic effect of barbiturates, and can be used to treat tension, anxiety, and insomnia. Its sedative effect also complements its analgesic effect.

3. Effects on the cardiovascular system
Dilation of coronary arteries: Corydalis yanhusuo can increase blood flow to the coronary arteries, improve blood supply to the myocardium, and have a protective effect against myocardial ischemia. This provides modern scientific evidence for the treatment of “chest obstruction and heartache” (coronary heart disease, angina pectoris).

Antiarrhythmic: Some alkaloids (such as berberine) have antiarrhythmic effects.

Lowering blood pressure: By inhibiting the vascular movement center and directly dilating blood vessels, it produces a mild antihypertensive effect.

4. Anti ulcer effect
Mechanism: Some alkaloids of Corydalis yanhusuo can inhibit gastric acid secretion and have a protective effect on the gastric mucosa.

Application: This explains why it can effectively treat “epigastric pain” and has a clear preventive and therapeutic effect on experimental gastric ulcers.

5. Anti inflammatory effect
The extract of Corydalis yanhusuo has inhibitory effects on various inflammatory models, such as increased capillary permeability and tissue edema, which is consistent with its traditional efficacy of “promoting blood circulation and dispersing blood stasis” to eliminate swelling and pain.

6. Muscle relaxation effect
Yanhusuo Yi Su has a certain relaxing effect on smooth muscle and skeletal muscle, which helps alleviate pain caused by muscle spasms.