Cyperus Rotundus (Xiang Fu) Extract Powder 10:1, 20:1, 50:1 TLC

Cyperus Rotundus (Xiang Fu) Extract Powder 10:1, 20:1, 50:1 TLC

The functions of Rhizoma Cyperi in traditional Chinese medicine include soothing the liver and relieving depression, regulating qi and relieving pain, regulating menstruation and relieving pain. Used for liver depression and qi stagnation, chest and rib distension pain, hernia pain, breast distension pain, spleen and stomach qi stagnation, abdominal distension, fullness pain, menstrual disorders, menstrual cramps.

INQUIRY
Cyperus Rotundus (Xiang Fu) Extract Powder 10:1, 20:1, 50:1 TLC
Other names:  Xiang Fu, Rhizoma Cyperi, Nutgrass Galingale Rhizome
Botanical source: Cyperus rotundus L
Part used: Dry rhizomes of Cyperus rotandus L, a plant in the Cyperaceae family. In autumn, dig and remove the hairs, boil or steam them in boiling water, and then dry them in the sun.
Specification: 10:1, 20:1, 50:1 TLC
Appearance: Brownish yellow fine powder
Particle size: 95% pass 80 mesh size

Cyperus Rotundus (Xiang Fu) Extract Powder Production Flowchart
Cyperus Rotundus (Xiang Fu) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1st Reflux Extraction(10 times water,2 Hrs) – 2nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators warehousing

Specification Sheet of
Cyperus Rotundus (Xiang Fu) Extract Powder
Product name: Xiang Fu Extract
Specification: 10:1 TLC
Part used: Dry tender branches of Cinnamomum cassia Presl
Solvent used: Hot water
Process: Raw materials crushed, extracted, concentrated and spray-dried to powder
Non GMO according to regulation (EC) 1829/2003 and 1830/2003 or United States requirements. Non allergen according to Directive 2007/68 amending Annex IIIa to Directive 2000/13/EC and US Food allergen labelling and consumer protection act 2004.
Heavy Metals:      
Lead: NMT 3ppm Cadmium: NMT 1ppm
Arsenic: NMT 2ppm Mercury: NMT 1ppm
Residual solvents: Comply to USP
Pesticides residues: Conform to Regulation USP<561>
Microbiology:      
Total plate count: 10000cfu/g Max Yeasts and molds: 1000cfu/g Max
E.coli: Not detected in (g)10 Salmonella spp.: Not detected in (g)25
Staphylococcus aureus: Not detected in (g)10 Clostridium spp.: Not Present in 0.1 g of food
Organoleptic quality Method Specifications
Aspect: Visual : ( CQ-MO-148) Powder
Color: Visual : ( CQ-MO-148) Brownish
Flavor: Sensory: (CQ-MO-148) Characteristic
Analytical quality Method Specifications
Identification: TLC Conform
Loss on drying: USP <731> < 10%
Bulk density: USP <616> Method I 40 – 60 g/100mL
Particle size: Analytical sieving || USP <786> 100% through 80meshes
Packaging suitable for foodstuff.

Extended Reading
Cyperus Rotundus (Xiang Fu) Function and Efficacy Recorded in TCM
Xiangfu has a mild nature, with a pungent, slightly bitter, and slightly sweet taste, and belongs to the liver, spleen, and Sanjiao meridians. Its core function is to soothe the liver, regulate qi, regulate menstruation, and relieve pain.

1. Soothing the liver and relieving depression, regulating qi in a broad and moderate manner
Regarding the various symptoms caused by liver qi stagnation. The liver is responsible for regulating ejaculation, and likes to relieve symptoms but dislikes depression. Emotional instability and high stress can easily lead to liver qi stagnation.

Typical manifestations: rib distension and pain, bloating and tightness in the epigastric region (stomach and abdomen), belching, sighing, loss of appetite, depression or irritability.

Application: Xiangfu can pass through the qi of the liver, spleen, and three burners, and is particularly good at regulating liver qi. It is an essential medicine for treating rib pain, stomach pain, and abdominal distension. Often used in combination with Chaihu, Yujin, Baishao, etc. (such as Chaihu Shugan San).

2.Regulating menstruation and relieving pain
Regarding the issue: gynecological and menstrual related diseases.

Working principle: Women are born with the liver, and menstruation is closely related to the liver’s ability to regulate qi and blood. Stagnation of liver qi leads to poor circulation of qi and blood, resulting in menstrual disorders and dysmenorrhea.

Typical manifestations: menstrual cycle disorder, premenstrual or menstrual pain in the lower abdomen and breasts, amenorrhea, and poor menstrual flow.

Application: Xiangfu regulates menstruation and relieves pain by soothing the liver and regulating qi, promoting smooth flow of qi and blood. It is the core medication for treating dysmenorrhea, menstrual disorders, and premenstrual syndrome. Often combined with Angelica sinensis, Chuanxiong, Paeonia lactiflora, Artemisia argyi leaves, etc. (such as Ai Fu Nuan Gong Wan).

3.Other functions
Qi circulation and pain relief: Qi circulation leads to blood circulation, while qi stagnation leads to blood stasis. Xiangfu has strong energy, so it can also be used for pain caused by qi stagnation and blood stasis, such as chest tightness (chest tightness and heartache), bruises and pain from falls and injuries.

Antimiscarriage: For fetal restlessness caused by liver qi discomfort or fetal qi stagnation, Xiangfu can play a certain role in preventing miscarriage by regulating qi and regulating the middle, but it should be used with caution under the guidance of a doctor.

Modern Pharmacological Effects of Cyperus Rotundus (Xiang Fu)
Modern research suggests that the various pharmacological effects of Xiangfu are the result of the synergistic effects of its multiple components, mainly including:

Volatile oils: α – coumarin, β – coumarin, etc., are the main material basis for antispasmodic, analgesic, and estrogenic effects.
Flavonoids, such as resveratrol 3-O-rutinoside, are related to antioxidant, anti-inflammatory, and cardiovascular protection.
Triterpenes and alkaloids also contribute to their wide range of biological activities.

The following are its main modern pharmacological effects, which are mutually confirmed with traditional efficacy:
1. Significant estrogen like effects and bidirectional regulation of the uterus
Function: This is the core modern pharmacological foundation of Xiangfu as the “female head coach”. The volatile oil and extract of Xiangfu have mild estrogen like activity and can regulate the function of the hypothalamic pituitary ovarian axis.

Performance:
Inhibiting uterine contractions: For the uterus that is in a spasmodic or excited state (such as dysmenorrhea), Xiangfu can significantly inhibit its contractions and alleviate spasmodic pain.

The impact on the relaxed state of the uterus: For the relaxed state of the uterus, Xiangfu can have a slight excitatory effect, helping to restore its tension.

Corresponding traditional efficacy: regulating menstruation and relieving pain. This explains why it can effectively alleviate dysmenorrhea and regulate menstrual cycles.

2. Excellent antispasmodic, analgesic, and anti-inflammatory effects
Spasmodic: Xiangfu extract can relax various smooth muscles in the gastrointestinal tract, uterus, bronchi, etc., and relieve spasmodic pain.

Analgesia: Its volatile oil and alcohol extract have shown clear analgesic effects in various experimental models, such as hot plate method and acetic acid writhing method.

Anti inflammatory: It can inhibit the increase of capillary permeability, combat various inflammatory factors, and alleviate acute and chronic inflammatory reactions.

Corresponding traditional efficacy: regulating qi and relieving pain. This explains its relieving effect on pain symptoms such as liver and stomach qi stagnation (abdominal and rib distension pain) and dysmenorrhea.

3.Regulating the central nervous system (sedation, antidepressant)
Function: The volatile oil of Xiangfu has clear sedative, hypnotic, and anti anxiety effects. Research has shown that it may produce antidepressant effects by regulating monoamine neurotransmitters such as serotonin and dopamine.

Corresponding traditional efficacy: soothing the liver and relieving depression. This provides modern biological evidence for the symptoms of low mood, depression, irritability, insomnia, etc. caused by the stagnation of liver qi in traditional Chinese medicine.

4. The impact on the cardiovascular system
Heart strengthening and blood pressure lowering: Xiangfu extract can mildly enhance myocardial contractility, while producing a slow and long-lasting blood pressure lowering effect by dilating peripheral blood vessels.

Anti myocardial ischemia: It has a protective effect on experimental myocardial ischemia.

The impact on the digestive system

Gallbladder: Promotes bile secretion, aiding digestion and excretion.

Protecting gastrointestinal mucosa: has an inhibitory effect on experimental gastric ulcers.

5. Antibacterial and anti-inflammatory activity
The volatile oil of Xiangfu has inhibitory effects on various bacteria (such as Staphylococcus aureus, Shigella, etc.) and some fungi.

6. Antioxidant effect
Eliminate free radicals and alleviate oxidative stress damage.

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