The functions of Angelica sinensis in traditional Chinese medicine include nourishing blood and promoting blood circulation, regulating menstruation and relieving pain, moistening the intestines and promoting bowel movements. Used for blood deficiency and yellowing, dizziness and palpitations, menstrual disorders, menstrual disorders, dysmenorrhea, deficiency cold and abdominal pain, rheumatism and rheumatism, falls and injuries, abscesses and ulcers, intestinal dryness and constipation.

| Product name: | Dang Gui Extract | ||
| Specification: | 10:1 TLC | ||
| Part used: | Dried roots of Angelica sinensis(Oliv.)Diels | ||
| Solvent used: | Hot water | ||
| Process: | Raw materials crushed, extracted, concentrated and spray-dried to powder | ||
| Non GMO according to regulation (EC) 1829/2003 and 1830/2003 or United States requirements. Non allergen according to Directive 2007/68 amending Annex IIIa to Directive 2000/13/EC and US Food allergen labelling and consumer protection act 2004. | |||
| Heavy Metals: | |||
| Lead: | NMT 3ppm | Cadmium: | NMT 1ppm |
| Arsenic: | NMT 2ppm | Mercury: | NMT 1ppm |
| Residual solvents: | Comply to USP | ||
| Pesticides residues: | Conform to Regulation USP<561> | ||
| Microbiology: | |||
| Total plate count: | 10000cfu/g Max | Yeasts and molds: | 1000cfu/g Max |
| E.coli: | Not detected in (g)10 | Salmonella spp.: | Not detected in (g)25 |
| Staphylococcus aureus: | Not detected in (g)10 | Clostridium spp.: | Not Present in 0.1 g of food |
| Organoleptic quality | Method | Specifications | |
| Aspect: | Visual : ( CQ-MO-148) | Powder | |
| Color: | Visual : ( CQ-MO-148) | Brownish | |
| Flavor: | Sensory: (CQ-MO-148) | Characteristic | |
| Analytical quality | Method | Specifications | |
| Identification: | TLC | Conform | |
| Loss on drying: | USP <731> | < 10% | |
| Bulk density: | USP <616> Method I | 40 – 60 g/100mL | |
| Particle size: | Analytical sieving || USP <786> | 100% through 80meshes | |
| Packaging suitable for foodstuff. | |||
Extended Reading
Chinese Angelica (Dang Gui) Function and Efficacy Recorded in TCM
Danggui, known as the “holy herb in the blood” and the “leader of women’s health”, holds a high position in traditional Chinese medicine. It has a sweet, spicy, and warm nature, and belongs to the liver, heart, and spleen meridians. Its core function can be summarized as “nourishing blood and promoting blood circulation, regulating meridians and relieving pain”, and extending to multiple effects such as moistening the intestines and promoting bowel movements. The following is a detailed analysis of the functions of Angelica sinensis:
1.Nourishing blood – essential medicines for nourishing blood
Mechanism: Angelica sinensis has a moisturizing texture, a sweet and strong taste, and is specialized in nourishing Yin blood. It is the most commonly used medicine for treating blood deficiency syndrome.
Symptoms: pale or pale complexion, dizziness and blurred vision, palpitations and palpitations, pale lip and nail color.
Application:
Often combined with Rehmannia glutinosa, Paeonia lactiflora, and Ligusticum chuanxiong to form the blood replenishing basic formula “Siwu Tang”.
Used for anemia caused by various reasons, postpartum blood deficiency, and blood deficiency after major illnesses.
2.Promote blood circulation and regulate menstruation
Mechanism: Angelica sinensis has a pungent taste and can be used to promote blood circulation, dispel blood stasis, and replenish blood, making it “nourishing without stagnation, alive without harm”.
Symptoms: menstrual disorders, dysmenorrhea, amenorrhea, postpartum abdominal pain, etc.
Application:
For menstrual cramps and blood clots caused by blood stasis, it is often used together with peach kernels and safflower.
For those with blood deficiency, blood stasis, and cold coagulation, it is often used interchangeably with cassia twigs and wuzhuyu.
This is the main reason why Angelica sinensis is known as the “leader of women’s health”, and it may be used in almost all gynecological menstrual disease prescriptions.
3. Pain relief
Mechanism: Traditional Chinese Medicine believes that ‘if there is no connection, it will cause pain; if there is no glory, it will cause pain’. Danggui can treat the pain of blood stasis caused by “obstruction” by promoting blood circulation, and can also treat the pain of blood deficiency and lack of nourishment caused by “lack of glory” by supplementing blood.
Performance:
Blood stasis pain: such as traumatic injury, rheumatoid arthritis pain (joint pain), postpartum abdominal pain.
Blood deficiency pain: such as abdominal pain caused by deficiency cold.
Application: Often used in conjunction with blood activating painkillers such as Danshen, frankincense, and myrrh, or as an isothermal tonic with ginger and lamb.
4. Moisturize the intestines and promote bowel movements
Mechanism: Essence and blood share the same origin. Blood deficiency can lead to deficiency of body fluids, loss of intestinal lubrication, and thus constipation. Danggui nourishes blood, produces fluids, and thus moistens and smooths the intestines.
Performance: Suitable for constipation caused by blood deficiency and intestinal dryness, commonly seen in elderly, weak, postpartum, and chronically ill individuals. The symptoms include dry and difficult bowel movements, accompanied by pale complexion, dizziness, palpitations, and other blood deficiency symptoms.
Application: Often used in conjunction with laxatives such as Cistanche deserticola and hemp seeds, such as “Jichuan decoction”.
Modern Pharmacological Effects of Chinese Angelica (Dang Gui)
The pharmacological activity of Angelica sinensis is mainly attributed to its complex chemical composition, including volatile oils (such as ligustilide), organic acids (such as ferulic acid), polysaccharides, flavonoids, etc.
The following are the main modern pharmacological effects of Angelica sinensis, which have been classified and summarized for you:
1. Effects on blood and hematopoietic system
This is the most direct modern interpretation of the “blood nourishing and blood activating” effect of Angelica sinensis.
Promote hematopoietic function:
Main ingredient: Angelica polysaccharide.
Mechanism: Stimulate macrophages, fibroblasts, and other cells in the bone marrow hematopoietic microenvironment to produce and release hematopoietic growth factors, thereby promoting the proliferation and differentiation of hematopoietic stem/progenitor cells.
Reflection: It has a significant promoting effect on the generation of red blood cells, white blood cells, and platelets. This provides a pharmacological basis for the treatment of various types of anemia (blood deficiency).
Anticoagulation and Antithrombotic Formation:
Main ingredient: Ferulic acid.
Mechanism: Inhibit platelet activation and aggregation; Extend prothrombin time and thrombin time.
Reflection: This explains its efficacy in promoting blood circulation and removing blood stasis, which is used for preventing and treating blood stasis.
Bidirectional regulation effect:
It is worth noting that Angelica sinensis exhibits bidirectional regulation of the blood system under different ingredients and processing methods. Its water-soluble components can inhibit blood clotting and promote blood circulation, while its volatile oil components may promote platelet aggregation at high concentrations; When processed into Danggui charcoal, it exhibits a stronger hemostatic effect.
2. The bidirectional regulatory effect of the palace
This is the key to explaining that Angelica sinensis can not only regulate menstruation and relieve pain, but also be used for preventing miscarriage.
Mechanism:
Inhibition of uterus (spasmolysis): The volatile oil components of Angelica sinensis have a significant relaxing effect on the contracted uterus, which can counteract uterine spasms caused by acetylcholine and other factors.
Exciting the uterus: The non-volatile components of Angelica sinensis (such as water-soluble and alcohol soluble components) can enhance the rhythmic contractions of the uterus.
Application association:
When uterine spasms cause dysmenorrhea, its antispasmodic effect plays a role in relieving pain.
When there is a need to discharge blood stasis after childbirth or during menstruation, its stimulating effect on the uterus can promote contractions and clear the “endless lochia”. This bidirectional regulation is a precise manifestation of traditional Chinese medicine’s “regulating meridians”.
3. The effect on the cardiovascular and cerebrovascular system
Expand blood vessels and improve microcirculation: Angelica sinensis can dilate peripheral blood vessels, coronary arteries, and cerebral blood vessels, reduce resistance, and increase blood flow.
Antiarrhythmic: It has significant preventive and therapeutic effects on various experimental arrhythmias.
Protection of vascular endothelium and anti atherosclerosis: protect vascular endothelial cells and inhibit the formation of atherosclerotic plaque through antioxidant and anti-inflammatory effects.
4. Anti inflammatory, analgesic, and immune regulation
Anti inflammatory: It can inhibit the production and release of various inflammatory mediators, alleviate acute and chronic inflammatory reactions.
Analgesia: Its analgesic effect has been confirmed by various experimental models, involving both central and peripheral mechanisms.
Immune regulation:
Enhancing immunity: Angelica polysaccharides can significantly enhance the phagocytic function of macrophages, promote lymphocyte proliferation and antibody production, and improve the non-specific and specific immune functions of the body.
Immunosuppression: At the same time, it also has a certain regulatory effect on excessive immune reactions (such as allergic reactions).
5. Liver protection and anti pulmonary fibrosis
Liver protection: It has a clear protective effect on chemical liver damage (such as carbon tetrachloride and acetaminophen), can alleviate liver cell degeneration and necrosis, promote liver cell regeneration, and inhibit liver fibrosis.
Anti pulmonary fibrosis: Recent studies have found that Angelica sinensis can inhibit fibroblast proliferation and collagen deposition, and has an intervention effect on experimental pulmonary fibrosis, providing a new approach for the treatment of interstitial lung disease.
6. Neuroprotection and anti-aging
Neuroprotection: Angelica sinensis and its components have the potential to protect against neurological damage such as cerebral ischemia, Alzheimer’s disease, Parkinson’s disease, etc. The mechanisms involve antioxidant activity, inhibition of cell apoptosis, and reduction of inflammation.
Antioxidant and anti-aging: can effectively eliminate free radicals, reduce oxidative damage, and delay cellular aging.
7. Antitumor adjuvant effect
Research has found that polysaccharides from Angelica sinensis and ferulic acid have inhibitory effects on proliferation and induce apoptosis in various tumor cells.
Important reminder: The main value of Angelica sinensis in tumor treatment is reflected in adjuvant therapy, which improves patients’ quality of life and treatment tolerance by enhancing immune function, reducing bone marrow suppression and other side effects of radiotherapy and chemotherapy.