Glossy Privet Fruit (Nv Zhen Zi) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Nv Zhen Zi, Fructus Ligustri Lucidi, Glossy Privet Fruit, Ligustri Lucidi Fructus
【Botanical source】: Ligustrum lucidum Ait
【Part used】: Dry and ripe fruit of Ligustrum Lucidum Ait, a plant in the Oleaceae family. Harvesting fruits in winter when they are ripe, removing branches and leaves, steaming or blanching them in boiling water, and then drying them; Or dry it directly.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Glossy Privet Fruit (Nv Zhen Zi) Extract Powder Production Flowchart
Glossy Privet Fruit (Nv Zhen Zi) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Glossy Privet Fruit (Nv Zhen Zi) Extract Powder

Extended Reading
Glossy Privet Fruit (Nv Zhen Zi) Function and Efficacy Recorded in TCM
Ligustrum lucidum is a very important yin tonifying medicine in traditional Chinese medicine, especially known for nourishing the yin of the liver and kidneys. Its medicinal properties are peaceful, nourishing without dryness, and it is a representative of the clear and nourishing products.

Below is a detailed analysis of the role of Ligustrum lucidum in traditional Chinese medicine.

Ligustrum lucidum has a sweet and bitter taste, and a cool nature. Return to the liver and kidney meridians. Its core function is to nourish the liver and kidneys, and improve vision with black beard. Mainly targeting liver and kidney yin deficiency syndrome.

1. Nourish the liver and kidneys
This is the most essential and fundamental function of Ligustrum lucidum.

Function: Ligustrum lucidum has a moisturizing texture and can nourish the Yin fluid of the liver and kidneys. The liver and kidney are of the same origin, and kidney yin is the fundamental source of Yin fluid in the whole body. If liver yin is sufficient, the eyes will be clear and the muscles will be soft.

Indications:
Liver and kidney yin deficiency: manifested as dizziness and vertigo, soreness and weakness of the waist and knees, tinnitus and hearing loss, premature graying of the beard and hair, nocturnal emissions, and dry mouth and throat.

Yin deficiency and internal heat: Due to insufficient Yin fluid, relative Yang hyperactivity occurs, resulting in symptoms such as hot flashes, night sweats, and restlessness of the five hearts (fever in the palms, soles, and chest).

Modern correspondence: commonly used in hypertension, diabetes, climacteric syndrome, neurasthenia and other manifestations of liver and kidney yin deficiency.

2. Blacken the beard and hair
Function: Traditional Chinese medicine believes that “hair is not only in the blood, but also in the kidneys. The moisturizing and shedding of hair are closely related to the rise and fall of liver blood and kidney essence. Ligustrum lucidum nourishes the liver, kidneys, essence, and blood, allowing the hair and beard to be nourished and become black and shiny.

Indications: Early graying of beard and hair. Early graying of hair.

3. Improving eyesight
Function: “The liver opens the orifices to the eyes”. If the liver and kidney yin deficiency cannot ascend to the eyes, it can lead to decreased vision and blurred vision. Ligustrum lucidum improves vision by nourishing the liver and kidneys, injecting essence and blood into the eyes.

Indications: Obscure vision, blurred vision, cataracts, floaters, etc.

Modern Pharmacological Effects of Glossy Privet Fruit (Nv Zhen Zi)
The modern pharmacological research on Ligustrum lucidum is very in-depth, which fully verifies and enriches its traditional efficacy of nourishing the liver and kidneys, and improving vision from a scientific perspective. Its pharmacological activity mainly comes from its various active ingredients, including oleanolic acid, ursolic acid, ligustilide, polysaccharides, flavonoids, and phospholipids.

The following are the main modern pharmacological effects of Ligustrum lucidum:

1. Liver protective effect
This is one of the most prominent and thoroughly studied pharmacological effects of Ligustrum lucidum.

Key ingredients: Oleanolic acid and Ursolic acid.

Mechanism of action:
Combat chemical liver damage (such as caused by carbon tetrachloride, alcohol, etc.) and reduce serum transaminase levels.

Reduce liver cell degeneration and necrosis, promote liver cell regeneration and repair.

Anti liver fibrosis.

Clinical significance: It provides a solid scientific basis for the use of Ligustrum lucidum in the treatment of liver diseases such as hepatitis and fatty liver.

2. Regulating immune function
Ligustrum lucidum has a unique “bidirectional regulation” effect on immune function.

Enhancing immunity: Polysaccharides from Ligustrum lucidum are the main active ingredient. It can:

Enhance the phagocytic ability of macrophages.
Promote the proliferation and differentiation of T lymphocytes, and enhance cellular immune function.
Promote antibody production and enhance humoral immune function.

Inhibition of immunity (anti allergy): In cases of immune overactivity (such as allergic reactions, autoimmune diseases), certain components in Ligustrum lucidum (such as oleanolic acid) can also have anti allergy and immunosuppressive effects.

Clinical significance: This explains its effect of “strengthening the body and consolidating the foundation”, which is suitable for people with low immunity and may also have potential benefits for autoimmune diseases.

3. Antioxidant and anti-aging
This is a modern interpretation of its “nourishing yin” and “wuxufa” effects. Aging and many diseases are closely related to oxidative stress

Function: Flavonoids and phenolic compounds in Ligustrum lucidum can effectively scavenge free radicals (such as DPPH and hydroxyl radicals), inhibit lipid peroxidation, and protect cell membranes and DNA from oxidative damage.

Clinical significance: it helps to delay aging and prevent chronic diseases related to oxidative stress, such as atherosclerosis, neurodegenerative diseases, etc.

4. Hypoglycemic and lipid-lowering effects
Hypoglycemic effect: Extracts from Ligustrum lucidum can increase insulin sensitivity, improve insulin resistance, and may protect pancreatic beta cells, thereby exerting a hypoglycemic effect.

Lowering blood fat: it can significantly reduce the levels of serum total cholesterol, triglycerides and low-density lipoprotein (“bad” cholesterol), which is of positive significance for the prevention and treatment of atherosclerosis.

Clinical significance: It provides pharmacological basis for Ligustrum lucidum used in the treatment of diabetes (“diabetes” in TCM) and hyperlipidemia.

5. Antitumor effect
Mechanism: The active ingredients of Ligustrum lucidum (such as oleanolic acid and ursolic acid) exert anti-tumor effects through multiple pathways:

Inducing tumor cell apoptosis and cell cycle arrest.
Inhibit the invasion and metastasis of tumor cells.
Combined with chemotherapy drugs, it can enhance efficacy and reduce its toxic side effects.

Research status: It has inhibitory effect on a variety of cancer cells (such as liver cancer, lung cancer, breast cancer, etc.), and is a hot spot of current research, but most of them are in the experimental stage.

6. Effects on the cardiovascular system
Cardiotonic and Diuretic: Extracts of Ligustrum lucidum have the effects of enhancing myocardial contractility, dilating coronary arteries, improving myocardial ischemia, and diuresis.

Clinical significance: This provides clues for its potential application as an adjuvant therapy for heart failure and hypertension.

7. Antibacterial and anti-inflammatory effects
Antibacterial: It has inhibitory effects on various Gram positive and Gram negative bacteria (such as Staphylococcus aureus, Escherichia coli, etc.).

Anti inflammatory: can inhibit the release of inflammatory mediators and alleviate inflammatory reactions.

8. Neuroprotective effect
Preliminary studies have shown that extracts from Ligustrum lucidum may have a protective effect on neurons through antioxidant and anti apoptotic pathways, and have potential research value for neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.