Notoginseng (San Qi) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Radix Notoginseng, Tian Qi, San Qi, Sanchi, Pseudoginseng, Pseudoginseng Root
【Botanical source】: Panax notoginseng （ Burk.） F. H. Chen
【Part used】: Dried roots and rhizomes of Panax Notoginseng (Burk.) F.H. Chen, a plant in the Araliaceae family. Dig and wash before the autumn flowers bloom, separate the main roots, branch roots, and rhizomes, and then dry.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Notoginseng (San Qi) Extract Powder Production Flowchart
Notoginseng (San Qi) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Notoginseng (San Qi) Extract Powder

Extended Reading
Notoginseng (San Qi) Function and Efficacy Recorded in TCM

Sanqi is a very unique and precious medicinal herb in traditional Chinese medicine, known as the “gold does not exchange” and “divine herb of the south”. Its nature is sweet, slightly bitter, and warm. Return to the liver and stomach meridians. Its core characteristic is “stopping bleeding without leaving blood stasis, removing blood stasis without damaging the body”, which is not possessed by the vast majority of other blood activating or hemostatic drugs. The following are the detailed functions of Sanqi in traditional Chinese medicine:

1. Removing blood stasis and stopping bleeding (the most distinctive function)
Mechanism: Sanqi can promote coagulation, contract local blood vessels to stop bleeding; It can also disperse blood stasis inside and outside the blood vessels to promote blood circulation. This seemingly contradictory bidirectional regulatory effect makes it the preferred medicine for treating various bleeding syndromes, especially those with blood stasis.

Application:
Various types of bleeding inside and outside the human body: Whether taken orally or externally, it has a remarkable effect on coughing up blood, vomiting blood, nosebleeds (nosebleeds), rectal bleeding, urinary bleeding, metrorrhagia (excessive menstruation or non menstrual bleeding in women), and traumatic bleeding.

Characteristics: When used for bleeding syndrome, it can not only quickly stop bleeding, but also prevent blood stasis after stopping bleeding, avoiding the aftermath of “closing the door and leaving behind enemies”. This is precisely the key to its superiority over other hemostatic drugs.

2. Promote blood circulation and relieve pain
Mechanism: By exerting strong blood activating and stasis dispersing power, the blockage of qi and blood in the meridians is unblocked, thereby achieving the analgesic effect of “general rule without pain”.

Application:
Injuries caused by falls and bruises, as well as swelling and pain, are essential medications for orthopedics. In the famous “Yunnan Baiyao”, Sanqi is its main ingredient. For various sprains, contusions, and early stage swelling and pain of fractures, the effect is excellent.

Heart and abdominal pain, accumulation of symptoms: used for stomach pain, chest obstruction, and heartache caused by qi stagnation and blood stasis (such as angina pectoris). It can clear the cardiovascular system and relieve pain.

Dysmenorrhea and Amenorrhea: For blood stasis type dysmenorrhea and menstrual disorders, it has a good effect of removing blood stasis, relieving pain, and promoting menstruation.

3. Supplement deficiency and strengthen the body
Mechanism: The “Compendium of Materia Medica” records that “ginseng is the first to replenish qi, and Sanqi is the first to supplement blood.” Sanqi’s “supplement” is not like ginseng’s direct replenishment of qi, but rather through the elimination of blood stasis and the generation of new blood, clearing the pathological product of “blood stasis” in the body, promoting the smooth flow of qi and blood, and indirectly achieving the effect of blood supplementation. Modern research has also found that it can promote the proliferation of hematopoietic stem cells.

Application: Used for physical weakness, loss of appetite, neurasthenia, excessive fatigue, etc. It is commonly used in folk to stew chicken with panax notoginseng as a recuperation Tonic Diet after illness or postpartum.

4. Core position in cardiovascular and cerebrovascular diseases
This is the most important application expansion of Sanqi in modern traditional Chinese medicine. Its effect of “promoting blood circulation and removing blood stasis” perfectly corresponds to the mechanism of “anti thrombosis, improving microcirculation and stabilizing atherosclerotic plaque” in modern medicine.

Application:
Prevention and treatment of coronary heart disease and angina: can dilate coronary arteries and increase myocardial blood supply.

Treating cerebral infarction and its sequelae: can improve cerebral blood circulation.

Modern Pharmacological Effects of Notoginseng (San Qi)
The modern pharmacological research on Sanqi is very in-depth, and its excellent therapeutic effect has been scientifically fully verified. The main active ingredients of Panax notoginseng are saponins (mainly Panax notoginseng saponins), in addition to flavonoids, polysaccharides, amino acids, etc.

The following are the main modern pharmacological effects of Sanqi, which perfectly explain its traditional efficacy in traditional Chinese medicine:

1. Dual regulation of hemostasis and blood circulation (hematopoiesis)
This is the most magical characteristic of Sanqi, which is the traditional Chinese medicine’s “removing blood stasis and stopping bleeding”.

Hemostasis mechanism: Panax notoginseng saponins can shorten bleeding and clotting time, increase platelet count, enhance platelet function, and quickly stop bleeding in the early stages of injury.

Blood activating/anti thrombotic mechanism: At the same time, it can inhibit excessive platelet aggregation, promote fibrinolysis, and effectively prevent and dissolve thrombosis. This “bidirectional regulation” effect enables it to quickly stop bleeding without causing vascular blockage, avoiding the drawbacks of “stopping bleeding and retaining blood stasis”.

Promoting hematopoiesis: Panax notoginseng polysaccharides can stimulate the proliferation of hematopoietic progenitor cells and promote hematopoietic function, which is consistent with the traditional Chinese medicine theory of “removing blood stasis and generating novelty”.

2. Strong protective effect on the cardiovascular and cerebrovascular system
This corresponds to its modern application of “promoting blood circulation and relieving pain” in the treatment of chest obstruction and heartache.

Expand blood vessels and improve circulation: Panax notoginseng saponins can non specifically block receptor dependent calcium channels in vascular smooth muscle, dilate peripheral blood vessels and coronary arteries, lower blood pressure, increase coronary blood flow, and improve microcirculation.

Anti atherosclerosis: it can reduce the content of triglycerides and cholesterol in the blood, reduce the inflammatory reaction of the inner wall of blood vessels, and inhibit the formation of atherosclerotic plaque.

Protecting myocardium and brain tissue: It has a significant protective effect on myocardial ischemia and cerebral ischemia-reperfusion injury, and can reduce the infarct size. Its mechanism is related to antioxidant and inhibition of cell apoptosis.

3. Anti inflammatory and analgesic effects
This scientifically explains the principle of using it as an essential medicine in orthopedics to treat injuries caused by falls, bruises, swelling, and pain.

Anti inflammatory: Panax notoginseng saponins can significantly inhibit the production and release of various inflammatory mediators (such as prostaglandins, leukotrienes, etc.), and alleviate inflammatory reactions.

Analgesia: Its analgesic effect has been experimentally proven to be effective and suitable for various types of pain.

4. Liver protective effect
Sanqi can reduce serum transaminase, promote liver protein synthesis, alleviate liver fibrosis, and have a clear protective effect on chemical liver damage (such as alcohol and drugs).

5. Antitumor effect
Research has found that saponins from Panax notoginseng can exert anti-tumor effects through various pathways, such as inducing cancer cell apoptosis, inhibiting cancer cell proliferation and metastasis, and reversing cancer cell drug resistance. Often used as an adjuvant medication in cancer treatment to enhance efficacy and reduce side effects.

6. Antioxidant and anti-aging properties
Panax notoginseng saponins can effectively eliminate oxygen free radicals and have strong antioxidant capacity, which can alleviate the damage of oxidative stress to tissue cells and delay aging.

7. Regulating immunity
Panax notoginseng polysaccharides and saponins have a bidirectional regulatory effect on the immune system, which can enhance immunity when it is too low, and inhibit immune response when it is too high.

8. Lowering blood sugar
Research has shown that saponins from Panax notoginseng can increase tissue uptake and utilization of glucose, improve insulin sensitivity, and help lower blood sugar levels.