Peanut Coat(Skin) Extract Powder 10:1, 20:1, 50:1 TLC, proanthocyanidins/OPCs 95% UV
【Botanical source】: Arachis hypogaea L.
【Part used】: Skin/coat
【Specification】: 10:1, 20:1, 50:1 TLC, proanthocyanidins/OPCs 95% UV
【Extraction solvents】: Water
【Appearance】: Brownish fine powder
【Particle size】: 95% pass 80 mesh size
【Main ingredients】: Peanut skin (red coat) extract mainly contains rich polyphenolic substances, including anthocyanins (especially A-type structure), resveratrol, catechins, and tannins. In addition, it also contains flavonoids (such as quercetin), organic acids, and various minerals. These ingredients collectively endow it with powerful antioxidant, anti-inflammatory, and cardiovascular protective biological activities.
【Storage conditions】：Store at room temperature in a sealed manner, away from light, and in a ventilated, cool, and dry environment.
【Shelf life】： 24 months from the production date

Peanut Coat(Skin) Extract Powder Production Flowchart
Peanut Coat(Skin) raw materials -Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Peanut Coat(Skin) Extract Powder

Extended Reading
Modern Research on Peanut Coat(Skin) Extract Powder
Chemical Components

Peanut skins are exceptionally rich in bioactive polyphenols, constituting up to 15% of their dry weight. Key components include:

• Proanthocyanidins (PAs or Condensed Tannins): The most abundant (40-60%), primarily consisting of A-type procyanidin dimers, trimers, and higher polymers. This A-type linkage (C2-O-C7 or C2-O-C5) is less common than B-type and is considered pharmacologically distinctive.
• Flavonoids: Including catechins, epicatechins, and various flavonols like quercetin and kaempferol glycosides.
• Phenolic Acids: Significant amounts of chlorogenic, coumaric, ferulic, and ellagic acids.
• Stilbenes: Notably resveratrol and its analogs (e.g., arachidin-1, -2, -3), especially abundant in certain varieties and upon elicitation.
• Other: Isoflavones, vitamins, and minerals.

Health Benefits (Mechanisms & Key Findings)

PSE’s bioactivities stem from its potent antioxidant, anti-inflammatory, prebiotic, and enzyme-inhibitory properties.

1. Cardiovascular Health: Demonstrates strong ACE-inhibitory activity (potentially lowering blood pressure), reduces LDL oxidation, improves endothelial function, and inhibits platelet aggregation, reducing thrombotic risk.
2. Antidiabetic & Anti-obesity Effects: Potently inhibits digestive enzymes (α-amylase, α-glucosidase, pancreatic lipase), slowing carbohydrate and fat absorption. Studies show reduced postprandial blood glucose and triglyceride spikes. It also modulates adipogenesis.
3. Prebiotic & Gut Health: High-molecular-weight PAs are poorly absorbed but serve as prebiotics, promoting beneficial gut microbiota (e.g., Akkermansia, Bifidobacteria) and producing short-chain fatty acids, enhancing gut barrier function.
4. Neuroprotective Potential: In vitro and animal models suggest PSE’s antioxidants can cross the blood-brain barrier, reduce neuroinflammation, and protect against oxidative stress, showing promise for Alzheimer’s and Parkinson’s disease models.
5. Anticancer Properties: In vitro studies show pro-apoptotic, anti-proliferative, and anti-angiogenic effects against various cancer cell lines (e.g., breast, colon, prostate), primarily through induction of oxidative stress in cancer cells.

Interactions

• Anticoagulant/Antiplatelet Drugs (e.g., warfarin, clopidogrel): Potential risk due to PSE’s demonstrated antiplatelet and antithrombotic activity. Concurrent use may increase bleeding risk.
• Antihypertensive Drugs: May have additive effects with ACE inhibitors or other blood pressure medications due to its ACE-inhibitory activity.
• Antidiabetic Drugs: May enhance the glucose-lowering effect of medications like metformin or insulin, increasing hypoglycemia risk.
• Iron Absorption: Like other polyphenol-rich extracts, high doses may non-specifically chelate dietary non-heme iron, potentially affecting iron status with long-term use.

Contraindications, Warnings & Side Effects

• Contraindications: Known allergy to peanuts or legumes (cross-reactivity possible). Avoid if on heavy anticoagulant therapy without medical supervision.
• Warnings: Due to potent enzyme inhibition, individuals with malabsorption syndromes or nutrient deficiencies should use caution. Safety during pregnancy/lactation is not established.
• Side Effects: Generally recognized as safe (GRAS) at food-grade levels. High supplemental doses may cause mild gastrointestinal upset, nausea, or constipation due to astringency of tannins.

Applications

• Nutraceuticals & Dietary Supplements: In capsules or powders for antioxidant, cardiovascular, and metabolic health support.
• Functional Food & Beverage Ingredient: As a natural preservative and functional additive in health bars, shakes, teas, and baked goods.
• Cosmeceuticals: In anti-aging skincare formulations for its antioxidant and collagen-protective effects.
• Pharmaceutical Intermediates: As a source for isolating high-value A-type procyanidins and resveratrol.

References (Key Modern Reviews & Studies)

1. Yu, L., et al. (2016). “Peanut Skin Procyanidins: Composition and Antioxidant Activities as Affected by Processing.” Journal of Food Composition and Analysis, 44, 178-187.
2. Nepote, V., et al. (2020). “Peanut Skin as a Functional Ingredient: Its Bioactive Compounds and Potential Health Benefits.” Journal of Food Science and Technology, 57(10), 3547-3563.
3. Isanga, J., & Zhang, G. (2021). “Bioactive Components and Health Benefits of Peanut By-Products: A Review.” Food Reviews International, 38(5), 1017-1043.
4. Monagas, M., et al. (2009). “Insights into the Metabolism and Microbial Biotransformation of Dietary Flavan-3-ols and the Bioactivity of Their Metabolites.” Food & Function, 1(3), 233-253. (Seminal on PAs).
5. Ma, Y., et al. (2014). “Anti-inflammatory Effects of Peanut Skin Extract on LPS-stimulated RAW 264.7 Macrophages.” Journal of Agricultural and Food Chemistry, 62(52), 12700-12708.
6. Sarnoski, P.J., et al. (2012). “Separation and Characterisation of Proanthocyanidins in Virginia-type Peanut Skins by LC–MSⁿ.” Food Chemistry, 131(3), 927-939.
7. Shi, L., et al. (2022). “Peanut Skin Extract Ameliorates High-Fat Diet-Induced Atherosclerosis by Regulating Lipid Metabolism, Inflammation, and Gut Microbiota.” Nutrients, 14(5), 988.
8. Medina-Larque, A.S., et al. (2022). “Peanut Skin Extract Improves Glucose Homeostasis and Ameliorates Oxidative Stress in Mice Fed a High-Fat High-Sucrose Diet.” Antioxidants, 11(4), 747.

 Note: This summary is for informational purposes. It may interact with medications and is contraindicated in certain conditions. Consult a healthcare professional before therapeutic use, particularly regarding its estrogenic activity.