Pleurotus Citrinopileatus (Golden Oyster Mushroom) Extract Powder 10:1, 20:1, 50:1 TLC
【Botanical source】: Pleurotus citrinopileatus Singer
【Part used】: Frutingbody
【Specification】: 10:1, 20:1, 50:1 TLC,
【Extraction solvents】: Water
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size
【Main ingredients】:The main components of Pleurotus Citrinopileatus include polysaccharides (especially β – glucan), proteins and glycoproteins, dietary fiber, ergosterol (precursor of vitamin D2), phenolic antioxidants, and various minerals (such as potassium and selenium). These ingredients combine nutritional value with physiological activities such as immune regulation and antioxidant activity.
【Storage conditions】：Store at room temperature in a sealed manner, away from light, and in a ventilated, cool, and dry environment.
【Shelf life】： 24 months from the production date

Pleurotus Citrinopileatus (Golden Oyster Mushroom) Extract Powder Production Flowchart
Cactus raw materials -Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Pleurotus Citrinopileatus (Golden Oyster Mushroom) Extract Powder

Extended Reading

Modern Pharmacological Effects of Pleurotus Citrinopileatus (Golden Oyster Mushroom) Extract

Pleurotus citrinopileatus, commonly known as the golden oyster mushroom, is a culinary fungus increasingly studied for its medicinal properties. Its extract is rich in bioactive compounds, including polysaccharides (particularly β-glucans), glycoproteins, phenolic compounds, ergosterol (a precursor of vitamin D2), and specific lectins. Modern pharmacological research reveals a range of therapeutic potentials beyond its nutritional value.

Key Pharmacological Effects:

1. Immunomodulation & Antitumor Activity: The most prominent effect is attributed to its polysaccharide-protein complexes (e.g., PCPS). These compounds potently stimulate both innate and adaptive immunity by activating macrophages, enhancing natural killer (NK) cell activity, and promoting lymphocyte proliferation and cytokine production (e.g., TNF-α, IL-2, IFN-γ). This robust immunoenhancing activity underlies its significant antitumor and antimetastatic effects observed in various animal models, often through immune-mediated mechanisms rather than direct cytotoxicity.
2. Antioxidant & Anti-aging: The extract exhibits strong free radical scavenging activity (against DPPH, ABTS, and hydroxyl radicals) and reduces lipid peroxidation, primarily due to its phenolic content and certain polysaccharides. This systemic antioxidant capacity contributes to anti-aging effects, protecting cells from oxidative stress and potentially modulating age-related pathways.
3. Hepatoprotective: Studies demonstrate protective effects against chemical-induced liver injury (e.g., from carbon tetrachloride or ethanol). The extract reduces serum levels of liver enzymes (ALT, AST), attenuates hepatic lipid peroxidation, and enhances the activity of antioxidant enzymes like superoxide dismutase (SOD), thereby preserving liver function and structure.
4. Neuroprotective Potential: Emerging research suggests that P. citrinopileatus polysaccharides may have neuroprotective benefits. In models of cognitive impairment or neuronal injury, they help improve learning and memory, reduce neuronal apoptosis, and combat neuroinflammation, indicating potential for neurodegenerative disease management.
5. Antihyperlipidemic & Metabolic Regulation: The β-glucans and dietary fiber in the extract contribute to hypolipidemic effects. They can reduce serum total cholesterol, triglycerides, and low-density lipoprotein (LDL) levels while increasing high-density lipoprotein (HDL), aiding in the management of hyperlipidemia and associated cardiovascular risks.
6. Antimicrobial & Prebiotic: Some extracts show inhibitory activity against certain pathogenic bacteria and fungi. Furthermore, the non-digestible polysaccharides may act as prebiotics, promoting the growth of beneficial gut microbiota, which in turn supports overall gut health and systemic immunity.

Conclusion

Pleurotus citrinopileatus extract is a promising source of bioactive compounds with multi-target pharmacological actions. Its potent immunomodulatory and antitumor properties are of particular interest, supported by complementary antioxidant, hepatoprotective, and metabolic benefits. These findings position it as a valuable functional food and a potential adjunct in strategies for cancer prevention, immune support, and managing age- and lifestyle-related chronic diseases.

References

1. Chen, Y., et al. (2020). Structural characterization and immunomodulatory activity of a novel polysaccharide from Pleurotus citrinopileatus. International Journal of Biological Macromolecules, 164, 2926-2935.
2. Huang, H. Y., et al. (2021). Antioxidant and anti-inflammatory activities of polysaccharides from Pleurotus citrinopileatus on LPS-induced RAW264.7 macrophages. Journal of Food Biochemistry, 45(4), e13676.
3. Khan, M. A., et al. (2014). Hepatoprotective effect of Pleurotus citrinopileatus extract on carbon tetrachloride-induced liver injury in rats. Journal of Food Science and Technology, 51(9), 1873-1881.
4. Li, S., et al. (2018). Neuroprotective effects of Pleurotus citrinopileatus polysaccharides on oxidative stress and apoptosis in neuronal cells. Experimental and Therapeutic Medicine, 15(5), 4271-4278.
5. Ma, G., et al. (2022). A review on the nutritional composition, health benefits, and potential applications of golden oyster mushroom (Pleurotus citrinopileatus). Food Science & Nutrition, 10(3), 691-703.
6. Patel, Y., et al. (2012). Medicinal properties of Pleurotus species (oyster mushrooms): A review. World Journal of Fungal and Plant Biology, 3(1), 01-12. (Includes discussion on P. citrinopileatus).
7. Singdevsachan, S. K., et al. (2016). Mushroom polysaccharides as potential prebiotics: A review. Bioactive Carbohydrates and Dietary Fibre, 8, 34-42.
8. Wang, J., et al. (2015). Antitumor and immunomodulatory activities of a polysaccharide from Pleurotus citrinopileatus. Carbohydrate Polymers, 132, 274-279.
9. Xu, X., et al. (2019). Structural analysis and hypolipidemic activity of a novel polysaccharide from Pleurotus citrinopileatus. Process Biochemistry, 87, 229-236.
10. Zhang, Y., et al. (2017). Extraction, purification and anti-aging activity of polysaccharides from Pleurotus citrinopileatus. International Journal of Biological Macromolecules, 101, 553-560.

Note: This summary is for informational purposes. It may interact with medications and is contraindicated in certain conditions. Consult a healthcare professional before therapeutic use, particularly regarding its estrogenic activity.