Scutellaria baicalensis (Huang Qin) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Huang Qin, Baical Skullcap Root, Radix Scutellariae
【Botanical source】: Scutellaria baicalensis Georgi
【Part used】: Dry roots of Scutellaria baicalensis Georgi, a plant in the family Lamiaceae. Harvesting and digging in spring and autumn, removing roots and sediment, sun drying to remove rough skin, and sun drying.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size
Scutellaria baicalensis (Huang Qin) Extract Powder Production Flowchart
Scutellaria baicalensis (Huang Qin) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Scutellaria baicalensis (Huang Qin) Extract Powder

Extended Reading
Scutellaria baicalensis (Huang Qin) Function and Efficacy Recorded in TCM
Scutellaria baicalensis is one of the most commonly used heat clearing and detoxifying drugs in traditional Chinese medicine clinical practice. It has a bitter and cold taste, and is beneficial for the lungs, gallbladder, spleen, large intestine, and small intestine meridians. It has a wide range of effects, with the core being “clearing heat and dampness, purging fire and detoxifying”. It is particularly good at clearing heat pathogens and fire toxins in the upper burner (lungs, heart) and middle burner (spleen and stomach, liver and gallbladder).

1. Clear heat and dry dampness

This is one of the most important benefits of Scutellaria baicalensis, mainly used to treat various diseases caused by “dampness and heat”. Used for damp heat diarrhea and jaundice: Scutellaria baicalensis can clear the damp heat in the spleen, stomach, large intestine, and liver and gallbladder. It has good therapeutic effects on diarrhea and dysentery caused by common dampness and heat in summer (often accompanied by Huanglian, Pueraria lobata, etc.), as well as jaundice caused by liver and gallbladder dampness and heat (yellowing of skin and eyes), such as acute hepatitis, cholecystitis, etc.

Used for dampness, warmth, heat, dampness: manifested as fever, chest tightness, nausea, yellow urine, etc., often combined with talc, cardamom, etc.

2. Relieve fire and detoxify

Huangqin is good at clearing and releasing excess heat, especially good at clearing lung heat. Used for lung heat cough: This is the most classic application of Scutellaria baicalensis. It has a strong lung clearing effect on cough, phlegm yellow and viscous, sore throat, asthma, etc. caused by excessive lung heat. Often used in combination with mulberry bark, cicadas, etc. It is commonly used in modern times to treat acute bronchitis, pneumonia, etc.

Used for fever and high fever: In external febrile diseases, when there are symptoms such as high fever, restlessness, and strong pulse, it is often used together with heat clearing and purging gunpowder such as gardenia, coptis, gypsum, etc.

3. Cooling blood to stop bleeding

Huangqin’s cold nature can cool the blood and has a therapeutic effect on bleeding caused by excessive blood heat. Used for blood heat bleeding: such as vomiting blood, epistaxis (nosebleeds), rectal bleeding, uterine bleeding, etc., often used together with cooling blood hemostatic drugs such as Shengdi and Baimaogen.

4. Clearing heat and stabilizing pregnancy

In traditional Chinese medicine theory, fetal restlessness is sometimes caused by maternal blood heat, which disturbs the fetal element. Used for fetal heat discomfort: For symptoms such as fetal movement, slight vaginal bleeding, and restlessness due to heat in the body during pregnancy, Huangqin can clear blood heat to stabilize the fetus. Often combined with Atractylodes macrocephala to form the classic “Atractylodes macrocephala powder” with modifications.

Modern pharmacological research on Scutellaria baicalensis (Huang Qin)

The modern pharmacological research on Scutellaria baicalensis is very rich, and its main active ingredients are flavonoids, among which baicalin and baicalin are the most important. The following are the main aspects of modern pharmacological effects of Scutellaria baicalensis:

1. Antibacterial and antiviral effects

Antibacterial: Studies have shown that Scutellaria baicalensis has inhibitory effects on various Gram positive and Gram negative bacteria, such as Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Shigella, Escherichia coli, etc. This provides a scientific explanation for its treatment of respiratory and intestinal infections (such as dysentery).

Antivirus: Scutellaria baicalensis Georgi and its effective ingredients have broad spectrum antiviral activity, especially for influenza virus, respiratory syncytial virus, hepatitis virus (hepatitis B, hepatitis C), and even some coronaviruses. The main mechanism is to inhibit virus replication and entry into cells.

2. Anti inflammatory and immune regulatory effects

Anti inflammatory: This is one of the most prominent pharmacological effects of Scutellaria baicalensis. Baicalin can significantly inhibit the production and release of various inflammatory factors, such as tumor necrosis factor – α (TNF – α), interleukin-6 (IL-6), prostaglandin E2, etc. This directly confirms the principle of traditional Chinese medicine using it to treat inflammatory diseases such as “lung heat cough” and “sores, abscesses, swelling, and toxins”.

Immune regulation: Scutellaria baicalensis has a bidirectional regulatory effect on the immune system. It can both suppress excessive immune responses (which can be used to treat allergic and autoimmune diseases) and enhance the phagocytic function of macrophages to a certain extent.

3. Hepatoprotective and choleretic effects

Liver protection: Scutellaria baicalensis can alleviate chemical liver damage (such as caused by carbon tetrachloride and alcohol), and has a protective effect on acute and chronic hepatitis and liver fibrosis. Its mechanism includes anti-inflammatory, antioxidant, and inhibition of hepatic stellate cell activation.

Lidan: Scutellaria baicalensis can promote bile secretion and excretion, which is helpful in treating cholecystitis and jaundice. This is completely consistent with the use of traditional Chinese medicine to treat jaundice caused by “damp heat in the liver and gallbladder”.

4. Antioxidant and free radical scavenging effects

Baicalin and baicalin are powerful antioxidants that can effectively eliminate oxygen free radicals in the body and reduce the damage caused by oxidative stress to cells. This is related to various benefits such as anti-aging, protecting cardiovascular and cerebrovascular systems, and anti-tumor effects.

5. Antitumor effect

A large number of in vitro and animal experiments have shown that Scutellaria baicalensis extract and its flavonoids have inhibitory effects on a variety of cancer cells (such as lung cancer, liver cancer, colon cancer, breast cancer, etc.). The mechanism includes:
Inducing apoptosis of cancer cells
Inhibit cancer cell proliferation
Inhibit tumor angiogenesis
Reversing multidrug resistance in cancer cells

At present, Huangqin is often used as an adjuvant drug in tumor treatment to enhance the efficacy of radiotherapy and chemotherapy and reduce its side effects.

6. Cardiovascular and cerebrovascular protective effects
Protecting blood vessels: It has the effect of dilating blood vessels and lowering blood pressure.
Regulating blood lipids: can reduce serum total cholesterol, triglycerides, and low-density lipoprotein.
Anti atherosclerosis: protect vascular endothelial cells and delay the formation of atherosclerotic plaque through antioxidant, anti-inflammatory and other effects.

7. Protective effect on the nervous system
Research has found that baicalin has potential protective effects against neurodegenerative diseases such as cerebral ischemia (stroke) injury, Alzheimer’s disease, Parkinson’s disease, etc. Its mechanism is related to antioxidant, anti apoptotic, and anti-inflammatory reactions.

8. Anti allergic effect

Scutellaria baicalensis can inhibit the release of allergens such as histamine and can be used to treat allergic diseases such as asthma, allergic rhinitis, and eczema. This is partially consistent with the connotation of “clearing heat and detoxifying” in traditional Chinese medicine.