Teasel Root (Xu Duan) Extract Powder 10:1, 20:1, 50:1 TLC

Teasel Root (Xu Duan) Extract Powder 10:1, 20:1, 50:1 TLC

The functions of Teasel Root(Xu Duan) in traditional Chinese medicine include tonifying the liver and kidneys, strengthening muscles and bones, continuing broken wounds, and stopping collapse and leakage. Used for liver and kidney deficiency, soreness and weakness in the waist and knees, rheumatism and rheumatism, falls and falls, muscle injuries, fractures, collapse, and fetal leakage. Jiuxuduan is commonly used for rheumatism, rheumatism, and pain, as well as for injuries such as falls, falls, and muscle fractures. Salt is often used for soreness and weakness in the waist and knees.

INQUIRY
Teasel Root (Xu Duan) Extract Powder 10:1, 20:1, 50:1 TLC
Other names: Xu Duan, Radix Dipsaci, Chuan Duan, Himalayan Teasel Root
Botanical source: Dipsacus asper Wall. ex Henry
Part used: Dry roots of Dipsacus asper Wall. ex Henry, a plant in the family Dipsacaceae. Excavate in autumn, remove the roots and beard roots, dry over low heat until semi dry, pile up to “sweat” until the inside turns green, and then dry again.
Specification: 10:1, 20:1, 50:1 TLC
Appearance: Brownish yellow fine powder
Particle size: 95% pass 80 mesh size
Teasel Root (Xu Duan)Extract Powder Production Flowchart
Teasel Root (Xu Duan) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1st Reflux Extraction(10 times water,2 Hrs) – 2nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators warehousing

Specification Sheet of
Teasel Root (Xu Duan) Extract Powder
Product name: Xu Duan Extract
Specification: 10:1 TLC
Part used: Dried roots of Dipsacus asper Wall. ex Henry
Solvent used: Hot water
Process: Raw materials crushed, extracted, concentrated and spray-dried to powder
Non GMO according to regulation (EC) 1829/2003 and 1830/2003 or United States requirements. Non allergen according to Directive 2007/68 amending Annex IIIa to Directive 2000/13/EC and US Food allergen labelling and consumer protection act 2004.
Heavy Metals:
Lead: NMT 3ppm Cadmium: NMT 1ppm
Arsenic: NMT 2ppm Mercury: NMT 1ppm
Residual solvents: Comply to USP
Pesticides residues: Conform to Regulation USP<561>
Microbiology:
Total plate count: 10000cfu/g Max Yeasts and molds: 1000cfu/g Max
E.coli: Not detected in (g)10 Salmonella spp.: Not detected in (g)25
Staphylococcus aureus: Not detected in (g)10 Clostridium spp.: Not Present in 0.1 g of food
Organoleptic quality Method Specifications
Aspect: Visual : ( CQ-MO-148) Powder
Color: Visual : ( CQ-MO-148) Brownish
Flavor: Sensory: (CQ-MO-148) Characteristic
Analytical quality Method Specifications
Identification: TLC Conform
Loss on drying: USP <731> < 10%
Bulk density: USP <616> Method I 40 – 60 g/100mL
Particle size: Analytical sieving || USP <786> 100% through 80meshes
Packaging suitable for foodstuff.

Extended Reading
Teasel Root (Xu Duan) Function and Efficacy Recorded in TCM
Continuation of fracture, as the name suggests, means “continuation of fracture” and is an essential medicine in traditional Chinese medicine orthopedics. Its medicinal properties are mild, with a bitter and pungent taste, and it belongs to the liver and kidney meridians. Its function is not limited to bone setting, but also widely used in regulating the liver and kidneys, and preventing miscarriage.

The following are the core roles and indications of Xuduan in traditional Chinese medicine theory:

1. Nourish the liver and kidneys, strengthen muscles and bones

This is the most fundamental effect of Xuduan, which fundamentally strengthens bones and tendons by nourishing the liver and kidneys.

Mechanism of action: The liver controls the tendons and the kidneys control the bones. Continuing to enter the liver and kidney meridians can nourish the essence and blood of the liver and kidneys, thereby strengthening the muscles and bones.

Main applications:
Liver and kidney deficiency, waist and knee soreness: manifested as chronic lower back pain, knee weakness, and difficulty walking, often combined with Eucommia ulmoides, Achyranthes Achyranthes, Mulberry Parasitic, etc., such as the Xuduan Pill in the “Fu Shou Jing Fang”.

Rheumatic rheumatism and pain: Especially suitable for joint pain and poor flexion and extension caused by liver and kidney deficiency combined with rheumatic invasion. It can not only dispel rheumatism, but also strengthen muscles and bones, making it an excellent product for both “strengthening the body” and “dispelling evil”.

2. Promote blood circulation, unblock meridians, and strengthen tendons and bones
This is the reason for its name and also its iconic role in orthopedics.

Mechanism of action: Xin Wen Xing Xing Nen San can promote blood circulation, remove blood stasis, and promote blood circulation; Bitter and warm can strengthen muscles and bones, promote tissue regeneration and connection.

Main applications:
Injuries caused by falls, muscle injuries, and fractures are commonly used medications for treating fractures, ligament strains, and soft tissue injuries. Oral administration can promote blood circulation and relieve pain, while external application can reduce swelling. It is often used together with natural copper, ground beetle worm, drynaria, etc.

Blood stasis block: used for various reasons leading to poor blood flow and pain caused by blood stasis.

3. Ensure stability, secure the tire, and prevent collapse and leakage
This is an important application of continuity in gynecology.

Mechanism of action: Chong becomes a sea of blood, acting as the host cell fetus. Insufficient liver and kidney function can lead to insufficient consolidation of the Chong and Ren organs. Continuation can achieve the effects of stabilizing the fetus and stopping bleeding by nourishing the liver and kidneys and strengthening the Chong Ren system.

Main applications:
Fetal restlessness, habitual abortion: For fetal leakage and fetal restlessness caused by liver and kidney deficiency, Chong Ren instability, it is often compatible with Sangsheng, Cuscuta chinensis, ass hide glue, etc., such as the famous Shoutai Pill in the Medical Heart Reference Western Record.

Blood loss caused by collapse: Used for women with excessive menstrual bleeding and incomplete bleeding (collapse), because it has the advantages of nourishing the liver and kidneys, strengthening the Chong Ren, stopping bleeding without leaving blood stasis.

Modern Pharmacological Effects of Teasel Root (Xu Duan)
The modern pharmacological research on Xuduan is very rich, which scientifically confirms and deepens our understanding of its traditional effects, especially in promoting bone healing and protecting the reproductive system.

The following are the main modern pharmacological effects of Xuduan:

1. Promote bone healing and repair
This is the most direct modern scientific confirmation of the effectiveness of the “Continuation of Muscle and Bone” technique.

Mechanism of action:
Promoting osteoblast proliferation: Dipsacus extract can significantly stimulate the activity and proliferation of osteoblasts, promote the synthesis and mineralization of bone matrix (such as collagen), and accelerate new bone formation.

Improving local blood circulation: Its blood activating effect is reflected in promoting the regeneration of capillaries at the fracture site, improving blood supply, and providing sufficient nutrition for bone healing.

Regulating bone metabolism related factors: can upregulate the expression of bone morphogenetic proteins, alkaline phosphatase, and other factors that promote bone formation.

Application: Provides a precise pharmacological basis for the continued treatment of fractures, non unions, and osteoporosis.

2. Effects on the reproductive system
This part of the effect confirms its traditional efficacy of “stabilizing the fetus” and regulating Chong Ren.

For bidirectional regulation of the palace:
Inhibition of uterine contractions: Total saponins of Dipsacus suspensa have a significant relaxing effect on the smooth muscle of the uterus in non pregnancy or early pregnancy, and can counteract uterine rigidity induced by oxytocin and other factors, which is like a natural “pregnancy protectant”.

Exciting uterus: Interestingly, for the uterus with high estrogen levels in the body, interruption also shows a mild excitatory effect. This bidirectional regulatory ability enables it to better adapt to complex internal environments.

Estrogen like effects: Some components in Xuduan have weak estrogen like activity, which helps regulate endocrine function and has positive implications for maintaining pregnancy and female reproductive health.

Improving testicular function: Studies have shown that interruption also has a protective effect on the male reproductive system, improving sperm production function and enhancing sperm quality.

3. Anti inflammation, analgesia, and immune regulation
This is closely related to its effectiveness in treating rheumatism and rheumatism.

Anti inflammatory: Saponins from Panax notoginseng can significantly inhibit the production and release of various inflammatory factors (such as prostaglandins, tumor necrosis factor alpha, etc.), and have a clear anti-inflammatory effect on experimental arthritis, swelling, etc.

Analgesia: It can increase the pain threshold of experimental animals and demonstrate central and peripheral analgesic effects.

Immune regulation: Xuduan polysaccharides can enhance the phagocytic ability of macrophages, promote lymphocyte transformation, and thus enhance the non-specific immune function of the body.

4. Antioxidant and anti-aging
Function: Dipsacus extract has a strong ability to scavenge free radicals, such as superoxide anions and hydroxyl radicals.

Meaning: Oxidative stress is an important cause of aging and many chronic diseases. The continuous antioxidant effect helps to protect cells (including nerve cells, bone cells, etc.) from damage and delay the degeneration of tissues and organs, which supports its anti-aging concept of “tonifying the liver and kidneys, strengthening muscles and bones” from a modern medical perspective.

5. Other functions
Anti osteoporosis: Not only can it promote osteogenesis, but it can also inhibit the activity of osteoclasts, regulate bone metabolism bidirectionally, and effectively prevent and treat osteoporosis caused by estrogen deficiency and other reasons.

Protecting cardiovascular and cerebrovascular systems: It has the effects of dilating blood vessels, improving microcirculation, and reducing myocardial oxygen consumption, and has a protective effect against myocardial ischemia.

Antibacterial: In vitro experiments have shown that Xuduan has inhibitory effects on various bacteria such as Staphylococcus aureus.

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