White Peony Root (Bai Shao) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Bai Shao, Radix Paeoniae Alba, White Paeony Root, Shao Yao, Bai Shao Yao
【Botanical source】: Paeonia lactiflora Pall.
【Part used】: Dry roots of Paeonia lactiflora Pall, a plant in the Ranunculaceae family. In summer and autumn, dig, wash, remove the head, tail, and fine roots, boil in boiling water, remove the outer skin or peel, and then boil and dry.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

White Peony Root (Bai Shao) Extract Powder Production Flowchart
White Peony Root (Bai Shao) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of White Peony Root (Bai Shao) Extract Powder

Extended Reading
White Peony Root (Bai Shao) Function and Efficacy Recorded in TCM
White peony is the dried root of the peony plant in the Ranunculaceae family, and is one of the most commonly used medicines in traditional Chinese medicine clinical practice. It has a bitter and sour taste, slightly cold, and belongs to the liver and spleen meridians.

Its core function can be summarized as “nourishing blood and regulating meridians, softening the liver and relieving pain, tonifying yin and stopping sweating”. Its main functions revolve around “blood” and “liver”. The following are its specific functions and clinical applications:

1.Nourishing blood and regulating menstruation
Mechanism of action: Paeonia lactiflora is a good blood nourishing medicine, especially good at nourishing blood and blood, and is an essential medicine for regulating menstruation in gynecology.

Indicative symptoms:
Menstrual disorders, dysmenorrhea, and metrorrhagia (excessive menstruation or non menstrual bleeding): For menstrual problems caused by blood deficiency or liver depression, white peony is the basic medication.

Blood deficiency syndrome: When manifested as symptoms such as pale complexion, dizziness, and palpitations (heart palpitations), it is often combined with Radix Rehmanniae, Angelica sinensis, and Chuanxiong to form the first blood supplement formula, “Siwu Tang”.

2. Softening the liver and relieving pain
Mechanism of action: This is a very unique and important efficacy of Paeonia lactiflora. The liver is responsible for regulating ejaculation, with a preference for sexual pleasure and aversion to depression. If the liver blood is insufficient or the liver qi is not relaxed, it can lead to excessive liver qi (liver hyperactivity), transverse invasion of the spleen, and cause acute pain in various parts of the body. Paeonic acid can astringent, cold can clear heat, good at nourishing liver blood, calming liver yang, and thus relieving pain.

Indicative symptoms:
Pain in the ribs (liver area or both sides), epigastric pain (epigastric and abdominal), and limb spasms: often combined with licorice to form “Shao Yao Gan Cao Tang”. This formula is a classic combination for relieving pain and relieving spasms, and modern pharmacology has confirmed its excellent antispasmodic and analgesic effects.

Diarrhea and abdominal pain caused by disharmony between the liver and spleen: as the famous formula “Painful Diarrhea Essential Formula” uses white peony to soften the liver, relieve urgency, and relieve abdominal pain.

3. Stabilize liver yang
Mechanism of action: Insufficient liver blood can lead to hyperactivity of liver yang. White peony can nourish blood and nourish yin, thereby calming down the hyperactivity of liver yang.

Indicative symptoms:
Headache and dizziness: caused by liver yang hyperactivity, manifested as dizziness, tinnitus, red complexion, irritability, etc. Often used in combination with raw earth, Achyranthes, and ocher, such as’ Zhengan Xifeng Tang ‘.

4. Suppress Yin and Stop Sweating
Mechanism of action: Paeonia lactiflora has a sour taste and astringent properties, which can solidify and protect Yin fluids, preventing their leakage.

Indicative symptoms:
Self sweating and night sweats:
Self sweating (not naturally sweating due to fatigue or hot weather): It is often caused by qi deficiency and instability, and is often combined with cassia twigs, astragalus, and other herbs. For example, in “Guizhi Tang”, white peony and cassia twig are used to harmonize the body and guard against sweating.

Night sweats (sweating after falling asleep at night and stopping when waking up): mostly due to yin deficiency, often used in conjunction with nourishing yin and reducing sweating medicines such as dragon bones, oysters, and Schisandra chinensis.

Modern Pharmacological Effects of White Peony Root (Bai Shao)
The modern pharmacological research of Paeonia lactiflora is very rich, and its traditional effects (such as nourishing blood, softening liver, relieving pain, etc.) have clear scientific basis behind them. The main active ingredients of Paeonia lactiflora include monoterpenoid glycosides such as paeoniflorin, paeoniflorin, oxidized paeoniflorin, benzoyl paeoniflorin, as well as tannins, volatile oils, polysaccharides, etc. The following are the main modern pharmacological effects of Paeonia lactiflora:

1. Effects on the central nervous system
Sedation, analgesia, and anticonvulsant:
Paeoniflorin is the core component, and its combination with licorice flavonoids in licorice (i.e. “Shao Yao Gan Cao Tang”) has significant synergistic analgesic and antispasmodic effects.

The mechanism may be related to inhibiting the excitability of the central nervous system, regulating monoamine neurotransmitters (such as serotonin), and opioid receptors.

Antidepressants and Improving Learning and Memory:
Research has shown that total glucosides of Paeonia lactiflora have antidepressant effects on depression models such as chronic stress.
It can also improve the learning and memory abilities of Alzheimer’s disease model animals and has neuroprotective potential.

2. Spasmodic and regulatory effects on smooth muscles
This is a direct manifestation of the efficacy of “relieving pain with ease and urgency”.

Function: Paeonia lactiflora and its active ingredients can significantly inhibit smooth muscle spasms in various organs such as the intestine, uterus, and trachea.

Mechanism: It is mainly achieved through anticholinergic effects, blocking calcium ion channels, and directly acting on smooth muscle cells. This perfectly explains why it can effectively treat diseases such as irritable bowel syndrome, abdominal pain, and dysmenorrhea.

3. Anti inflammatory and immune regulatory effects
Bi directional immune regulation: This is one of the most prominent pharmacological properties of Paeonia lactiflora.

Inhibition of excessive immunity: Total glucosides of Paeonia lactiflora can inhibit excessive activation and proliferation of T lymphocytes, regulate the production of cytokines (such as interleukin-1, tumor necrosis factor – α, etc.), thereby suppressing excessive inflammation and immune response. This has shown good efficacy in the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.

Enhance weakened immunity: At the same time, it can promote the phagocytic function of macrophages, enhancing the body’s weakened immunity under certain conditions.

Anti inflammatory: exerting a wide range of anti-inflammatory effects by inhibiting the release of inflammatory mediators and signaling pathways, such as the NF – κ B pathway.

4. Liver protective effect
Function: White peony has a significant protective effect on chemical liver injury (such as caused by carbon tetrachloride and D-galactosamine) and immune liver injury.

Mechanism: including antioxidant activity, inhibition of inflammatory response, stabilization of liver cell membrane, promotion of liver cell regeneration, etc. This confirms its traditional theory of “nourishing and softening the liver”.

5. Effects on the cardiovascular system
Expanding blood vessels and lowering blood pressure: Paeonia lactiflora can dilate peripheral blood vessels, especially coronary arteries, and has a mild but persistent hypotensive effect.

Antiplatelet aggregation and antithrombotic: It can inhibit platelet aggregation and prevent thrombus formation, which is related to its “blood circulation” effect.

Protecting myocardium: It has a protective effect against myocardial injury caused by ischemia-reperfusion.

6. Antioxidant and anti-aging
The effective ingredients of Paeonia lactiflora have the ability to eliminate free radicals (such as DPPH, superoxide anion), reduce the damage of oxidative stress to cells and tissues, thus delaying aging, and have potential benefits for diseases related to oxidative stress (such as diabetes complications, neurodegenerative diseases).

7. Other functions
Regulating blood sugar and blood lipids: Studies have shown that it has the effect of assisting in lowering blood sugar and regulating lipid metabolism.

Anti tumor: some studies show that the extracts of paeony and paeoniflorin can inhibit the proliferation of some cancer cell lines (such as liver cancer, gastric cancer, breast cancer), which may be achieved by inducing apoptosis, inhibiting metastasis and other ways, but most of them are in the experimental research stage.

Protecting bones: It has an improvement effect on osteoporosis models, which may be achieved through anti-inflammatory and regulation of bone metabolism.