Poria (Fu Ling) Extract Powder 10:1, 20:1, 50:1 TLC
【Other names】: Fu Ling, Poria, Indian Buead
【Botanical source】: Poria cocos（Schw.）Wolf
【Part used】: Dry sclerotia of Poria cocos (Schw.) Wolf, a fungus in the family Polyporus. Excavate from July to September, remove sediment after excavation, and dry in the shade.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow fine powder
【Particle size】: 95% pass 80 mesh size

Poria (Fu Ling) Extract Powder Production Flowchart
Poria (Fu Ling) raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1^st Reflux Extraction(10 times water,2 Hrs) – 2^nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing

Specification Sheet of Poria (Fu Ling) Extract Powder

Extended Reading
Poria (Fu Ling) Function and Efficacy Recorded in TCM
Poria cocos is one of the most widely used medicinal materials in the clinical application of traditional Chinese medicine. It is known as the “Four Time Magic Medicine” and “Tonic Diet”. Its nature and taste are peaceful, nourishing but not harsh, and beneficial but not fierce. It can both strengthen the body and dispel evil, with diverse effects. The core function of Poria cocos is to “dispel dampness” and “strengthen the spleen”, and many of its benefits are derived from this.

1.Water retention and infiltration (primary function)
Characteristics: The medicinal properties are gentle, and it promotes diuresis without harming the vital energy. It is an essential medicine for treating edema and urinary disorders, and can be used in combination regardless of whether it is cold, heat, deficiency or excess, or belongs to the external or internal category.

Application: Used for edema, phlegm retention (such as dizziness, palpitations), diarrhea and other symptoms caused by water and dampness.

2. Strengthening the spleen and calming the heart
Strengthening the spleen: By dispelling dampness, it can strengthen the spleen and treat symptoms such as insufficient food intake, bloating, loose stools, and fatigue caused by spleen deficiency and excessive dampness.

Calm the nerves and tranquilize the mind: Especially suitable for palpitations, insomnia, and forgetfulness caused by heart and spleen deficiency, and loss of mental health.

Modern Pharmacological Effects of Poria (Fu Ling)
The modern pharmacological research of Poria cocos is very in-depth, and its traditional functions of “strengthening the spleen, promoting dampness, and calming the mind” have been widely scientifically verified, and many new biological activities have been discovered. The pharmacological effects of Poria cocos are the result of the synergistic action of multiple components:

Poria cocos polysaccharides: the core components of immune regulation, anti-tumor, and anti-aging.

Triterpenoid compounds (such as ferulic acid, dehydroferulic acid, etc.): the main active substances for diuresis, anti-inflammatory, hepatoprotective, and anti-tumor effects.

Other: It also contains choline, histidine, potassium salts, etc., all of which are involved in its comprehensive pharmacological effects.

The following is a systematic explanation of its main modern pharmacological effects:

 Core pharmacological effects (directly corresponding to traditional effects)

1.Diuretic action
Discovery: Poria cocos has a mild and long-lasting diuretic effect, which is not as strong as Western diuretics, but can effectively promote the excretion of electrolytes such as sodium, chloride, and potassium.

Mechanism: The main active ingredient is Poria cocos (a triterpenoid compound), which can activate the sodium pump (Na ⁺ – K ⁺ – ATPase) on the cell membrane and regulate the body’s water and salt metabolism.

Meaning: It directly confirms its traditional efficacy of “promoting diuresis and promoting diuresis”, providing a pharmacological basis for the treatment of edema and urinary incontinence.

2.Immune regulation and enhancement effects
Discovery: Poria cocos polysaccharides are one of the main active ingredients in Poria cocos, with significant immune enhancing functions.

Mechanism
Can enhance the phagocytic function of macrophages.
Promote the proliferation and differentiation of T lymphocytes and B lymphocytes.
Improve the level of body specific antibodies.

Meaning: It explains the role of “strengthening the body and consolidating the foundation”, that is, by enhancing the body’s immunity to resist diseases, reflecting the modern connotation of “strengthening the spleen” (traditional Chinese medicine “spleen” is the main transportation and includes immune function).

3. Calming and calming effects
Discovery: Poria cocos decoction has a significant sedative effect on the central nervous system, which can reduce spontaneous activity in experimental animals, counteract the excitement caused by caffeine, and synergize with the sedative and hypnotic effects of pentobarbital.

Meaning: Science has confirmed its traditional efficacy of “calming the heart and calming the mind”, providing a basis for treating insomnia and palpitations.

4.Hepatoprotective effect
Discovery: Poria cocos has a protective effect on liver damage caused by various chemical substances such as carbon tetrachloride, can reduce serum transaminase levels, prevent liver cell necrosis, and promote liver cell regeneration.

Mechanism: Related to antioxidant, anti-inflammatory, and stable liver cell membrane.

Meaning: Expanded the application of “strengthening the spleen”, as traditional Chinese medicine believes that “seeing liver diseases, knowing the transmission of liver to spleen, should first strengthen the spleen”, and protecting the liver is an extension of strengthening the spleen.

Expanded pharmacological effects (new discoveries in modern research)
1.Antitumor activity
Discovery: Poria cocos polysaccharides and Poria cocos triterpenoids have significant anti-tumor activity, which is a research hotspot.

Mechanism
Direct inhibition: Inhibits tumor cell proliferation and induces apoptosis (programmed cell death).

Indirect regulation: mainly through enhancing the body’s immune function (such as activating macrophages and natural killer cells NK), exerting a “host mediated” anti-tumor effect, rather than direct cytotoxic effects.

Reduce the side effects of radiotherapy and chemotherapy, such as increasing white blood cell count and improving patients’ quality of life.

Meaning: As an adjuvant therapy drug for anti-tumor treatment, it has broad prospects.

2.Anti inflammatory and antioxidant effects
Discovery: Poria cocos extract can inhibit the production of various inflammatory factors such as TNF – α and IL-6, and has the ability to clear free radicals and enhance antioxidant enzyme activity.

Meaning: Its “diuresis” effect is partially related to anti-inflammatory effects; The antioxidant effect is the common basis for its multiple benefits such as anti-aging, liver protection, and cardiovascular protection.

3.The effect on the digestive system
Discovery: It can relax the smooth muscles of the gastrointestinal tract, inhibit gastric acid secretion, and have a preventive and therapeutic effect on experimental gastric ulcers.

Meaning: It confirms the efficacy of “strengthening the spleen and stomach” and can be used to regulate digestive disorders.

4. Anti aging effect
Discovery: Poria cocos can increase the activity of superoxide dismutase (SOD), reduce lipid peroxidation products (such as MDA), and protect cells from oxidative damage.

Meaning: Consistent with the traditional record of “prolonging life”, it is commonly used in anti-aging health products.

5. Cardiovascular protective effect
It was found that it had certain effects on lowering blood sugar, blood pressure and preventing atherosclerosis.