Cornus Officinalis Extract Powder(Dogwood fruit, Shan Zhu Yu) 10:1, 20:1, 50:1 TLC
Cornus officinalis has the effect of tonifying the liver and kidney, astringent and astringent, not only benefiting kidney essence, but also aiding kidney yang.
Cornus Officinalis Extract Powder(Dogwood fruit, Shan Zhu Yu) 10:1, 20:1, 50:1 TLC
【Botanical source】: Cornus officinalis Sieb. et Zucc.
【Part used】: It is the dry and mature flesh of the Cornus officinalis Sieb. et Zucc. in the dogwood family. Distributed in Yunnan, Shanxi, Jiangsu, Zhejiang, Anhui, Jiangxi, Shandong, Henan, Hunan, Sichuan, Shaanxi, Gansu and other places in China.
【Functions in TCM】: It has the effect of tonifying the liver and kidney, astringency and firmness removing. Commonly used for dizziness, tinnitus, low back and knee pain, impotence and ejaculation, frequent enuresis and urination, vaginal discharge, sweating collapse, internal heat and thirst quenching.
【Specification】: 10:1, 20:1, 50:1 TLC
【Appearance】: Brownish yellow powder
【Particle size】: 95% pass 80 mesh size
Cornus Officinalis Extract Production Flowchart
Cornus officinalis raw materials – natural air drying–Coarse powder(40 mesh) -Low temperature water extraction – 1st Reflux Extraction(10 times water,2 Hrs) – 2nd Reflux Extraction8 times water,1.5 Hrs) – 3rd Reflux Extraction(6 times water,1 Hrs) – Extraction Solution-combine&Filtrate-Concentrate-Extractum-spray drying – screening – packaging – detection of physical and chemical indicators – warehousing
Specification of Cornus Officinalis Extract
| Item | Standard | Test method |
| Appearance | Brownish Yellow fine powder | Visual & Organoleptic |
| Specification | 10:1 | TLC |
| Particle size | 80 mesh | Pass 80 mesh size screen |
| Ash | <13% | 2g/525℃/3hrs |
| Moisture | <7% | 5g/100℃/2.5hrs |
| Heavy metals | As <1.0ppm Pb<2.0PPM Hg<0.2ppm Cd<1.0ppm | Atomic Absorption |
| Microbiological Control | Total Plate Count<10,000cfu/g, Yeast & Mold<100cfu/g, E.Coli<10cfu/g. |
AOAC |
| Packing | 1kg/bag, 5kg/bag, or 25kg/fiber drum (D* H, 40*50cm),
It can also be packaged according to the requirements of customers, and all the packaging materials meet the standards of Chinese Pharmacopoeia 2010. |
|
Extended Reading
Chemical Composition of Cornus Officinalis
Volatile components include: palmitic acid, benzyl cinnamate, isobutanol, isoamyl alcohol, trans linalool oxide, elemene, furfural, methyl eugenol, isoasarone β- Phenylethanol.
Glycosides and aglycones include cornus glycoside, monoglycoside, swertiamarin, brucine, as well as ursolic acid, iridoid terpenes, glucose, fructose, and sucrose.
The fruit of Cornus officinalis still contains tannin, gallic acid, malic acid, tartaric acid, and vitamin A.
The fatty oil in the seeds of Cornus officinalis includes palmitic acid, oleic acid, and linoleic acid.
Pharmacological Action of Cornus Officinalis
1. Effects on the immune system:
1) Cornus officinalis polysaccharides have a significant promoting effect on immune response, activating natural killer cells (NK) and macrophage systems, stimulating the secretion of interleukin-1 (IL-I), tumor necrosis factor (TNF), and 7-interferon (IFN), regulating the production of interleukin-2 (IL-2), and 2.5mg/ml can increase lymphocyte transformation by 90%.
2. The anti-inflammatory effect: Cornus officinalis polysaccharides is significant in relieving pain caused by heat and chemical stimuli, and has a significant inhibitory effect on acute and chronic inflammatory reactions; It has an inhibitory effect on capillary permeability.
3. Antibacterial effect: Use the extract of Cornus officinalis to determine the antibacterial activity of several common food microorganisms. The results showed that the extract of Cornus officinalis had significant antibacterial effects on bacteria and some yeast.
4. Hypoglycemic effect: Cornus officinalis has the effect of treating diabetes. The alcohol extract of cornus officinalis not only has obvious hypoglycemic effect on adrenaline or alloxan induced diabetes rats, but also has hypoglycemic effect on streptozotocin induced diabetes rats, but has no obvious effect on blood sugar of normal rats. The effective ingredients of the hypoglycemic effect of Cornus officinalis are ursolic acid and oleanolic acid.
5. Effects on vascular endothelial cells and myocardial cells: The effective ingredients of Cornus officinalis can resist the morphological changes of myocardial cells caused by high blood sugar, improve cell survival rate, and increase the activity of superoxide dismutase in myocardial cells damaged by blood sugar, reduce the content of malondialdehyde, a product of lipid peroxidation, and exude lactate dehydrogenase and glutamic oxalate transaminase.
6. Anti arrhythmic effect: In the study of the anti arrhythmic effect of Cornus officinalis, it was found that the total extract of Cornus officinalis, ethyl acetate extract, and residual extract of Cornus officinalis all have very obvious anti arrhythmic effects. Its anti arrhythmic effect may be related to prolonging myocardial action potential, increasing the absolute value of resting potential, and reducing sinus node autonomy.
